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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 88 0 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 49.67599869 23.67700005 Tm 0 Tr [(CD)-1(K1)1(2)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 115.02100372 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 225.46099854 23.67700005 Tm 0 Tr [( )] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 236.46099854 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 -88 43.75799942 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -88 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT 1 0 0 -1 -35.5 61.9640007 Tm [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -11.875 61.9640007 Tm [(CDK12)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 18.90699768 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 71.40699768 61.9640007 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.65699768 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CDK1)1(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.89099884 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.26499939 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.91499329 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.28900146 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.8480072 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.22200012 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.01800537 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CRK7;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.88600159 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.26000214 12.82499981 Tm [(CRKR;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.52600098 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.90000153 12.82499981 Tm [(CRKRS;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.99000549 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.36399841 12.82499981 Tm [(hC)-1(DK)1(12)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.03799438 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001000110012000F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0014000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CDK12)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.15699768 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 216.83399963 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0016000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 250.3730011 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 283.9119873 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E001F00200021000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Rat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 317.45098877 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002200230024000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 350.98999023 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700120025000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 384.5289917 m 416.75 384.5289917 l 416.75 415.72900391 l -1.45000005 415.72900391 l h f* Q q 1 0 0 1 0 384.5289917 cm /P <> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 415.72900391 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 443.66799927 cm q 1 g 0.375 0.75 m 190.7749939 0.75 l 190.7749939 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 191.7749939 -0.25 l 191.7749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 191.5249939 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 191.5249939 172.3500061 l h f* Q q 1 0 0 1 191.1499939 0 cm -0.625 -0.25 m 232.2749939 -0.25 l 232.2749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(CrkRS)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.42700005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.92700005 11.72200012 Tm [(\(Cdc2-related)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.52400208 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.02400208 11.72200012 Tm [(ki)-1(na)1(se)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.77799988 11.72200012 Tm [(arg)1(in)-1(ine/se)-1(rine-rich,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.48199463 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.98199463 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(lso)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.28299999 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.78300095 27.3220005 Tm [(designat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.7009964 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.2009964 27.3220005 Tm [(CRK7)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.08799744 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.58799744 27.3220005 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.86499786 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.36499786 27.3220005 Tm [(CRKR)1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.85499573 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.35499573 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.91600037 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.41600037 27.3220005 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.93699646 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.43699646 27.3220005 Tm [(ubiquito)1(us)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.61000061 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.30699921 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.80699921 42.92200089 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.02899933 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.52899933 42.92200089 Tm [(ap)1(pears)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.68299866 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.18299866 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.25800323 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.75800323 42.92200089 Tm [(localize)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.68400574 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.18400574 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.25900269 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.75900269 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.75999451 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.25999451 42.92200089 Tm [(nuc)-1(leu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.07800293 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.57800293 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.30300045 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80300045 58.52199936 Tm [(link)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.03899956 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.53900146 58.52199936 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.1230011 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.6230011 58.52199936 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.90000153 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.40000153 58.52199936 Tm [(splicin)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.31500244 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.81500244 58.52199936 Tm [(machine)-1(r)1(y)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.69099426 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.19099426 58.52199936 Tm [(Crk)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(RS)] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.06999969 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.56999969 74.12200165 Tm [(belongs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.00999832 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.50999832 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.58499908 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.08499908 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.08599854 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.58599854 74.12200165 Tm [(serine)-1(/th)1(re)-1(o)1(n)-1(ine)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.94000244 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.44000244 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.74699402 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.24699402 74.12200165 Tm [(ki)-1(na)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.10599995 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.60599995 89.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.68799973 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.18799973 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.46500015 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.96500015 89.72200012 Tm [(Cdc2/)-1(Cd)1(k)-1(x)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.61699677 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.11699677 89.72200012 Tm [(subf)1(amily)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.82499695 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.32499695 89.72200012 Tm [(CrkRS)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.7519989 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.2519989 89.72200012 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.93400574 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.43400574 89.72200012 Tm [(ext)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(en)-1(s)1(i)-1(v)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.04400063 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.54400063 105.3219986 Tm [(pro)1(lin)-1(e-rich)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.67199707 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.17199707 105.3219986 Tm [(regions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.30000305 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.80000305 105.3219986 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.02200317 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.52200317 105.3219986 Tm [(resem)-1(b)1(le)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.02000427 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.52000427 105.3219986 Tm [(SH)-1(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.95300293 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.45300293 105.3219986 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 120.92199707 Tm [(WW)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.57299995 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.07300186 120.92199707 Tm [(do)1(main)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.90000153 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.40000153 120.92199707 Tm [(binding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.54399872 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.04399872 120.92199707 Tm [(sites,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.39700317 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.89700317 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.17399597 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.67399597 120.92199707 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.19500732 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.69500732 120.92199707 Tm [(RS)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.76499939 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.26499939 120.92199707 Tm [(do)1(main)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.09199524 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.22200012 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.72200012 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.28300095 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.78300095 136.52200317 Tm [(chara)1(c)-1(terist)1(ic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.45500183 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.95500183 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.79699707 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.29699707 136.52200317 Tm [(splicin)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.21200562 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.71200562 136.52200317 Tm [(fa)1(c)-1(t)1(ors.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.16400146 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.66400146 136.52200317 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.47099304 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.97099304 136.52200317 Tm [(pro)1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.04699993 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.54700089 152.12199402 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.63499832 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.13499832 152.12199402 Tm [(do)1(main)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.96199799 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.46199799 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.30400085 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.80400085 152.12199402 Tm [(CrkRS)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.23100281 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.73100281 152.12199402 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.29200745 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.79200745 152.12199402 Tm [(89)-1(%)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.35400391 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.85400391 152.12199402 Tm [(identical)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.28900146 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.78900146 152.12199402 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.86399841 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.36399841 152.12199402 Tm [(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(he)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.64799976 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.14799976 167.72200012 Tm [(CHED)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.93299866 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.43299866 167.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.73999786 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.23999786 167.72200012 Tm [(ki)-1(na)1(se)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.4940033 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.9940033 167.72200012 Tm [(also)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.25100708 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.75100708 167.72200012 Tm [(designat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.66900635 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.16900635 167.72200012 Tm [(CDC2L5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.24000549 167.72200012 Tm [( )] TJ ET EMC Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 191.1499939 0.75 m 191.1499939 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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