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0 0 -1 -110 43.75799942 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -110 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT 1 0 0 -1 -57.5 61.9640007 Tm [<00030004>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -33.875 61.9640007 Tm [(ED)-1(A)] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -13.58799744 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 38.91200256 61.9640007 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 44.16200256 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(EDA)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 101.39600372 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 103.76999664 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 129.41999817 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 131.79400635 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 175.35299683 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 177.727005 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 215.522995 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ED)-1(1)1(;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 82.71800232 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 87.8030014 12.82499981 Tm [(HED)-1(;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 108.74099731 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 113.8259964 12.82499981 Tm [(ED)-1(A)1(1;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 139.61999512 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 144.70500183 12.82499981 Tm [(ED)-1(A)1(2;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 170.49899292 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 175.58399963 12.82499981 Tm [(HED)-1(1)1(;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 201.84399414 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 206.92900085 12.82499981 Tm [(ODT)-1(1)1(;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 233.58900452 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 238.67399597 12.82499981 Tm [(XHED)-1(;)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 265.06201172 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 270.14700317 12.82499981 Tm [(ECT)-1(D1;)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 300.58099365 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 305.66598511 12.82499981 Tm [(XLHE)-1(D;)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 336.46899414 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 341.5539856 12.82499981 Tm [(ED)-1(1)1(-)-1(A)1(1;)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 375.88400269 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 380.96899414 12.82499981 Tm [(ED)-1(1)1(-)-1(A)1(2;)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 415.29901123 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 0 30.49699783 Tm [(ED)-1(A)1(-A1;)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 35.08399963 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 37.45800018 30.49699783 Tm [(ED)-1(A)1(-A2;)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 72.54199982 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 74.91600037 30.49699783 Tm [(ST)-1(HA)1(GX1)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 114.87000275 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 167.69500732 cm /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 201.23399353 cm /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0014>] TJ ET EMC /P <</MCID 60 >> BDC BT 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ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ED)-1(A)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 80.66200256 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 268.31201172 cm /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 301.85101318 cm /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 335.39001465 cm /P <</Lang (zh-CN) /MCID 86 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002200230024000D>] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 368.9289856 cm /P <</Lang (zh-CN) /MCID 91 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 402.46798706 m 416.75 402.46798706 l 416.75 433.66799927 l -1.45000005 433.66799927 l h f* Q q 1 0 0 1 0 402.46798706 cm /P <</MCID 97 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 98 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 99 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 433.66799927 cm /P <</MCID 100 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 461.60699463 cm q 1 g 0.375 0.75 m 173.5249939 0.75 l 173.5249939 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 174.5249939 -0.25 l 174.5249939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 101 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 102 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 174.2749939 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 174.2749939 156.75 l h f* Q q 1 0 0 1 173.8999939 0 cm -0.625 -0.25 m 249.5249939 -0.25 l 249.5249939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 103 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(The)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 15.80700016 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)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 81.09200287 27.3220005 Tm [(can)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 96.12599945 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 100.62599945 27.3220005 Tm [(be)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 111.48000336 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 115.98000336 27.3220005 Tm [(cl)-1(eaved)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 148.55700684 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 153.05700684 27.3220005 Tm [(by)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 163.56900024 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 168.06900024 27.3220005 Tm [(furin)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 188.11199951 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 192.61199951 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 201.68699646 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 206.18699646 27.3220005 Tm [(pro)1(duc)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(e)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 5.10599995 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 9.60599995 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 14.58100033 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 19.08099937 42.92200089 Tm [(sec)-1(reted)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 55.62599945 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 60.12599945 42.92200089 Tm [(fo)1(rm.)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 83.0039978 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 87.5039978 42.92200089 Tm [(The)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 103.31099701 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 107.81099701 42.92200089 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 145.31799316 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 149.81799316 42.92200089 Tm [(pro)1(tein)-1(,)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 183.29100037 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 187.79100037 42.92200089 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 212.88800049 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 217.38800049 42.92200089 Tm [(belo)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ngs)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 15.46899986 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 19.96899986 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 29.04400063 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 33.54399872 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 47.54499817 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 52.04499817 58.52199936 Tm [(tumor)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 78.53500366 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 83.03500366 58.52199936 Tm [(ne)-1(crosis)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 118.08599854 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 122.58599854 58.52199936 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 147.70500183 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 152.20500183 58.52199936 Tm [(fa)1(mi)-1(ly,)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 180.45300293 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 184.95300293 58.52199936 Tm [(acts)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 201.96000671 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 206.46000671 58.52199936 Tm [(as)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 215.60099792 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 220.10099792 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 225.07600403 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 229.57600403 58.52199936 Tm [(ho)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(mot)1(rime)-1(r)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 40.31499863 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 44.81499863 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 61.09199905 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 65.59200287 74.12200165 Tm [(may)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 83.76300049 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 88.26300049 74.12200165 Tm [(be)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 99.11699677 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 103.61699677 74.12200165 Tm [(involved)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 139.98599243 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 144.48599243 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 152.42700195 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 156.92700195 74.12200165 Tm [(ce)-1(ll-ce)-1(ll)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 189.63999939 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 194.13999939 74.12200165 Tm [(signaling)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 233.07099915 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(during)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 28.43700027 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 32.93700027 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 46.93799973 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 51.43799973 89.72200012 Tm [(development)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 108.43499756 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 112.93499756 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 121.77700043 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 126.27700043 89.72200012 Tm [(ec)-1(t)1(odermal)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 175.07400513 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 179.57400513 89.72200012 Tm [(org)1(ans.)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 211.34199524 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 215.84199524 89.72200012 Tm [(Defec)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ts)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 7.51900005 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 12.01900005 105.3219986 Tm [(in)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 19.95999908 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 24.45999908 105.3219986 Tm [(th)1(is)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 39.91600037 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 44.41600037 105.3219986 Tm [(gene)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 65.93199921 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 70.43199921 105.3219986 Tm [(are)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 83.94999695 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 88.44999695 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 93.42500305 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 97.92500305 105.3219986 Tm [(cause)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 122.23100281 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 126.73100281 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 135.57299805 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 140.07299805 105.3219986 Tm [(ec)-1(t)1(odermal)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 188.86999512 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 193.36999512 105.3219986 Tm [(dyspla)1(sia,)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 234.87600708 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(anhid)1(rotic,)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 45.79999924 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 50.29999924 120.92199707 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 75.39700317 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 79.89700317 120.92199707 Tm [(is)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 86.45800018 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 90.95800018 120.92199707 Tm [(also)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 108.21499634 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 112.71499634 120.92199707 Tm [(kn)-1(o)1(wn)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 141.53399658 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 146.03399658 120.92199707 Tm [(as)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 155.17500305 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 159.67500305 120.92199707 Tm [(X-link)-1(ed)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 195.4730072 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 199.9730072 120.92199707 Tm [(hypo)1(hidr)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(ot)1(ic)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 15.9829998 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 20.4829998 136.52200317 Tm [(ec)-1(t)1(odermal)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 69.27999878 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 73.77999878 136.52200317 Tm [(dyspla)1(sia.)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 115.28600311 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 119.78600311 136.52200317 Tm [(Se)-1(v)1(e)-1(ra)1(l)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 150.72399902 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 155.22399902 136.52200317 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 196.14599609 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 200.64599609 136.52200317 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 234.21600342 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 40.34199905 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 44.84199905 152.12199402 Tm [(many)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 68.55899811 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 73.05899811 152.12199402 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 109.99900055 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 114.49900055 152.12199402 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 151.65899658 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 156.15899658 152.12199402 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 176.5059967 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 181.0059967 152.12199402 Tm [(been)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 202.51300049 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 207.01300049 152.12199402 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 232.70300293 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 237.20300293 152.12199402 Tm [(f)] TJ ET EMC Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 156.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 173.8999939 0.75 m 173.8999939 156.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 156.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 157.125 m 423.17498779 157.125 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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