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g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(CDK7)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 101.58499908 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 154.08500671 12.82499981 Tm [(   )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 169.83500671 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CDK7)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 106.56900024 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 108.94300079 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 134.59300232 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 136.96699524 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 180.52600098 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 182.8999939 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 220.69599915 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CAK)1(1,)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 88.07099915 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 90.44499969 12.82499981 Tm [(HCAK)1(,)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 116.73600006 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 119.11000061 12.82499981 Tm [(MO15,)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 148.30299377 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 150.67700195 12.82499981 Tm [(ST)-1(K)1(1,)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 174.01499939 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 176.38900757 12.82499981 Tm [(CDKN)1(7,)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 208.62199402 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 210.9960022 12.82499981 Tm [(p39MO15)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 253.72900391 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0010000D>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CDK7)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 85.83499908 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000D>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140015>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0018>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0019000D>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B001C000F000D>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001D0004>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 70 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002200230024000D>] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00060007001C0025000D>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 81 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 82 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 84 >> BDC BT 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 151.7749939 0.75 l 151.7749939 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 152.7749939 -0.25 l 152.7749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 152.5249939 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 152.5249939 172.3500061 l h f* Q q 1 0 0 1 152.1499939 0 cm -0.625 -0.25 m 271.2749939 -0.25 l 271.2749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 87 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 247.7480011 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 252.2480011 11.72200012 Tm [(cy)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(cl)-1(in-d)1(e)-1(p)1(e)-1(nd)1(e)-1(nt)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 65.76899719 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 70.26899719 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 101.5759964 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 106.0759964 27.3220005 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 133.16400146 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 137.66400146 27.3220005 Tm [(\(CDK)1(\))] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 162.26499939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 166.76499939 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 195.01300049 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 199.51300049 27.3220005 Tm [(CDK)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 218.102005 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 222.602005 27.3220005 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 248.68400574 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 253.18400574 27.3220005 Tm [(m)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(embers)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 31.99699974 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 36.49700165 42.92200089 Tm [(are)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 50.01499939 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 54.51499939 42.92200089 Tm [(hig)1(hly)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 80.90899658 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 85.40899658 42.92200089 Tm [(similar)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 113.60399628 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 118.10399628 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 127.17900085 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 131.67900085 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 145.67999268 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 150.17999268 42.92200089 Tm [(gene)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 171.69599915 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 176.19599915 42.92200089 Tm [(pro)1(duc)-1(t)1(s)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 214.43699646 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 218.93699646 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 227.77900696 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 232.27900696 42.92200089 Tm [(Sacc)-1(ha)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(romyce)-1(s)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 36.14099884 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 40.64099884 58.52199936 Tm [(ce)-1(revisiae)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 82.56500244 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 87.06500244 58.52199936 Tm [(cdc)-1(28,)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 114.56999969 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 119.06999969 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 135.34700012 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 139.84700012 58.52199936 Tm [(Sc)-1(h)1(izosaccharo)1(my)-1(ce)-1(s)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 232.46200562 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 236.96200562 58.52199936 Tm [(po)1(mb)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(e)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 5.10599995 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 9.60599995 74.12200165 Tm [(cdc)-1(2,)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 31.83399963 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 36.33399963 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 52.61100006 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 57.11100006 74.12200165 Tm [(are)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 70.6289978 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 75.1289978 74.12200165 Tm [(kn)-1(o)1(wn)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 103.94799805 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 108.44799805 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 117.52300262 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 122.02300262 74.12200165 Tm [(be)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 132.8769989 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 137.3769989 74.12200165 Tm [(impor)1(tant)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 180.33799744 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 184.83799744 74.12200165 Tm [(regulat)1(ors)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 228.73100281 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 233.23100281 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 242.07299805 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 246.57299805 74.12200165 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 260.98300171 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(cy)-1(cle)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 21.29199982 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 25.79199982 89.72200012 Tm [(pro)1(gression.)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 79.15899658 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 83.65899658 89.72200012 Tm [(This)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 100.92099762 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 105.42099762 89.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 136.72799683 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 141.22799683 89.72200012 Tm [(fo)1(rms)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 166.10499573 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 170.60499573 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 175.58000183 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 180.08000183 89.72200012 Tm [(tr)1(i)-1(meric)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 213.14900208 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 217.64900208 89.72200012 Tm [(complex)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 254.12800598 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 18.39599991 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 22.89599991 105.3219986 Tm [(cy)-1(clin)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 47.02199936 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 51.52199936 105.3219986 Tm [(H)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 58.48300171 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 62.98300171 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 79.26000214 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 83.76000214 105.3219986 Tm [(MAT1,)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 111.48899841 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 115.98899841 105.3219986 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 141.08599854 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 145.58599854 105.3219986 Tm [(func)-1(t)1(ions)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 185.49299622 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 189.99299622 105.3219986 Tm [(as)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 199.13400269 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 203.63400269 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 208.60899353 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 213.10899353 105.3219986 Tm [(Cdk-a)1(c)-1(t)1(i)-1(v)1(at)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ing)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 13.69799995 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 18.19799995 120.92199707 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 45.2859993 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 49.7859993 120.92199707 Tm [(\(CAK)1(\).)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 76.02999878 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 80.52999878 120.92199707 Tm [(It)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 86.52899933 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 91.02899933 120.92199707 Tm [(is)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 97.58999634 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 102.08999634 120.92199707 Tm [(an)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 112.61100006 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 117.11100006 120.92199707 Tm [(esse)-1(nt)1(ial)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 154.31900024 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 158.81900024 120.92199707 Tm [(component)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 208.50799561 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 213.00799561 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 221.8500061 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 226.3500061 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 240.35099792 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 244.85099792 120.92199707 Tm [(tr)1(an)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(scriptio)1(n)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 37.27399826 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 41.77399826 136.52200317 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 66.89299774 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 71.39299774 136.52200317 Tm [(TFIIH)-1(,)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 95.7519989 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 100.2519989 136.52200317 Tm [(th)1(at)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 117.47399902 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 121.97399902 136.52200317 Tm [(is)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 128.53500366 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 133.03500366 136.52200317 Tm [(involved)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 169.40400696 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 173.90400696 136.52200317 Tm [(in)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 181.84500122 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 186.34500122 136.52200317 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 240.92900085 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 245.42900085 136.52200317 Tm [(initi)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(at)1(ion)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 21.98999977 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 26.48999977 152.12199402 Tm [(and)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 42.76699829 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 47.26699829 152.12199402 Tm [(DNA)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 67.77200317 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 72.27200317 152.12199402 Tm [(repair.)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 99.53600311 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 104.03600311 152.12199402 Tm [(This)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 121.29799652 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 125.79799652 152.12199402 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 157.10499573 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 161.60499573 152.12199402 Tm [(is)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 168.16600037 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 172.66600037 152.12199402 Tm [(th)1(ought)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 207.47900391 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 211.97900391 152.12199402 Tm [(to)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 221.05400085 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 225.55400085 152.12199402 Tm [(serve)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 248.09399414 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 252.59399414 152.12199402 Tm [(as)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 261.73498535 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(a)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 4.9749999 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 9.47500038 167.72200012 Tm [(direct)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 34.0359993 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 38.5359993 167.72200012 Tm [(link)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 53.77199936 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 58.27199936 167.72200012 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 95.34400177 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 99.84400177 167.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 113.84500122 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 118.34500122 167.72200012 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 162.57600403 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 167.07600403 167.72200012 Tm [(of)] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 175.91799927 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 180.41799927 167.72200012 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 235.0019989 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 239.5019989 167.72200012 Tm [(and)] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 255.77900696 167.72200012 Tm [( )] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 152.1499939 0.75 m 152.1499939 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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