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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 93.22100067 23.67700005 Tm 0 g [(BATF)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 145.37399292 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 322.07800293 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(BATF)] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 76.85299683 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 160.85299683 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(BATF)] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 84.72799683 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 87.10199738 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 120.30400085 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 122.6780014 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 182.65800476 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 185.03199768 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 219.5059967 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 17 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 18 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(SF)-1(A2)1(;)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 86.85600281 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 89.23000336 12.82499981 Tm [(B-ATF;)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 116.98200226 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 119.35600281 12.82499981 Tm [(BATF1;)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 149.21499634 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 151.58900452 12.82499981 Tm [(SF)-1(A-2)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 175.8500061 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 29 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 30 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 31 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 32 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 270.37298584 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(ll)] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 15.15999985 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 17.5340004 12.55799961 Tm [(length)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 44.6609993 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 47.03499985 12.55799961 Tm [(fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 73.3259964 12.55799961 Tm [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 75.69999695 12.55799961 Tm [(protein)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 107.08200073 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 132.67500305 0.75 l 132.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.67500305 -0.25 l 133.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 57 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.42500305 16.35000038 l h f* Q q 1 0 0 1 133.05000305 0 cm -0.625 -0.25 m 294.125 -0.25 l 294.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 61 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ba)1(sic)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 21.79700089 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 26.29700089 11.72200012 Tm [(leu)-1(cine)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 56.90499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 61.40499878 11.72200012 Tm [(zip)1(pe)-1(r)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 88.26399994 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 92.76399994 11.72200012 Tm [(ATF-like)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 127.72699738 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 132.227005 11.72200012 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 186.81100464 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 191.31100464 11.72200012 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 216.42999268 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 132.67500305 0.75 l 132.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.67500305 -0.25 l 133.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 73 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.42500305 16.35000038 l h f* Q q 1 0 0 1 133.05000305 0 cm -0.625 -0.25 m 294.125 -0.25 l 294.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 75 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(SFA2;)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 23.75200081 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 28.25200081 11.72200012 Tm [(B-ATF;)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 56.23199844 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 60.73199844 11.72200012 Tm [(BATF)-1(1;)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 90.09600067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 94.59600067 11.72200012 Tm [(SFA-2)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 120.07499695 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 132.67500305 0.75 l 132.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.67500305 -0.25 l 133.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.42500305 16.35000038 l h f* Q q 1 0 0 1 133.05000305 0 cm -0.625 -0.25 m 294.125 -0.25 l 294.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q16)-1(52)-1(0)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 33.72399902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 132.67500305 0.75 l 132.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.67500305 -0.25 l 133.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 87 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 90 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.42500305 16.35000038 l h f* Q q 1 0 0 1 133.05000305 0 cm -0.625 -0.25 m 294.125 -0.25 l 294.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 91 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(32)-1(29)-1(4)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 132.67500305 0.75 l 132.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.67500305 -0.25 l 133.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 93 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 94 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.42500305 16.35000038 l h f* Q q 1 0 0 1 133.05000305 0 cm -0.625 -0.25 m 294.125 -0.25 l 294.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 132.67500305 0.75 l 132.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.67500305 -0.25 l 133.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 111 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 114 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.42500305 16.35000038 l h f* Q q 1 0 0 1 133.05000305 0 cm -0.625 -0.25 m 294.125 -0.25 l 294.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 115 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 132.67500305 0.75 l 132.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.67500305 -0.25 l 133.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 119 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 120 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.42500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.42500305 16.35000038 l h f* Q q 1 0 0 1 133.05000305 0 cm -0.625 -0.25 m 294.125 -0.25 l 294.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 121 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 132.67500305 0.75 l 132.67500305 94.34999847 l 0.375 94.34999847 l h f* Q q -0.625 -0.25 m 133.67500305 -0.25 l 133.67500305 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 133 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 50.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 134 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 50.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.42500305 0.75 m 426.17498779 0.75 l 426.17498779 94.34999847 l 133.42500305 94.34999847 l h f* Q q 1 0 0 1 133.05000305 0 cm -0.625 -0.25 m 294.125 -0.25 l 294.125 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 135 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(nuc)-1(lear)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 211.15899658 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 215.65899658 11.72200012 Tm [(ba)1(sic)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 237.45599365 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 241.95599365 11.72200012 Tm [(leu)-1(cine)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 272.56399536 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 277.06399536 11.72200012 Tm [(zi)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(pp)1(e)-1(r)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 20.03899956 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 24.53899956 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 55.84600067 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 60.34600067 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 77.56800079 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 82.06800079 27.3220005 Tm [(belongs)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 116.50800323 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 121.00800323 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 130.08299255 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 134.58299255 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 148.58399963 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 153.08399963 27.3220005 Tm [(AP)1(-1/)-1(A)1(T)-1(F)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 194.21200562 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 198.71200562 27.3220005 Tm [(superfa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 248.79600525 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 253.29600525 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 262.13800049 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 266.63800049 27.3220005 Tm [(tr)1(an)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(scriptio)1(n)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 37.27399826 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 41.77399826 42.92200089 Tm [(fa)1(c)-1(t)1(ors.)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 73.22599792 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 77.72599792 42.92200089 Tm [(The)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 93.53299713 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 98.03299713 42.92200089 Tm [(leu)-1(cine)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 128.64100647 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 133.14100647 42.92200089 Tm [(zip)1(pe)-1(r)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 160 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 164.5 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 173.34199524 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 177.84199524 42.92200089 Tm [(th)1(is)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 193.29800415 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 197.79800415 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 229.10499573 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 233.60499573 42.92200089 Tm [(mediat)1(e)-1(s)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 272.89700317 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 277.39700317 42.92200089 Tm [(di)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(merizat)1(ion)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 45.78699875 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 50.28699875 58.52199936 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 68.68299866 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 73.18299866 58.52199936 Tm [(members)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 113.61299896 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 118.11299896 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 126.95500183 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 131.45500183 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 145.45599365 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 149.95599365 58.52199936 Tm [(Jun)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 164.61199951 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 169.11199951 58.52199936 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 195.19400024 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 199.69400024 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 208.53599548 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 213.03599548 58.52199936 Tm [(pro)1(tein)-1(s)1(.)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 250.67500305 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 255.17500305 58.52199936 Tm [(This)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 272.43701172 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 276.93701172 58.52199936 Tm [(p)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(rot)1(e)-1(in)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 25.55900002 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 30.05900002 74.12200165 Tm [(is)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 36.61999893 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 41.11999893 74.12200165 Tm [(th)1(ought)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 75.93299866 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 80.43299866 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 89.50800323 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 94.00800323 74.12200165 Tm [(be)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 104.86199951 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 109.36199951 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 114.33699799 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 118.83699799 74.12200165 Tm [(ne)-1(g)1(ative)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 155.79899597 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 160.29899597 74.12200165 Tm [(regulat)1(or)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 200.02600098 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 204.52600098 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 213.36799622 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 217.86799622 74.12200165 Tm [(AP)1(-1/)-1(A)1(T)-1(F)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 258.9960022 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 263.4960022 74.12200165 Tm [(tr)1(ans)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(criptiona)1(l)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 40.47800064 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 44.97800064 89.72200012 Tm [(eve)-1(nt)1(s.)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 75.14600372 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 208.79998779 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 133.05000305 0.75 m 133.05000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 133.05000305 17.10000038 m 133.05000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 133.05000305 33.45000076 m 133.05000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 133.05000305 49.80000305 m 133.05000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 133.05000305 66.15000153 m 133.05000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 133.05000305 82.5 m 133.05000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 133.05000305 98.84999847 m 133.05000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 133.05000305 115.19999695 m 133.05000305 208.79998779 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 208.79998779 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 209.17498779 m 426.92498779 209.17498779 l S Q Q q 1 0 0 1 0 592.67901611 cm Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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