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/GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(CDC)-1(4)1(2E)-1(P)1(2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 133.42399597 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 185.92399597 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 196.42399597 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CDC42EP2)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 127.90699768 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 130.28100586 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 155.93099976 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 158.30499268 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 201.86399841 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 204.23800659 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 242.03399658 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CDC)-1(4)1(2)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 91.3010025 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 93.67500305 12.82499981 Tm [(effe)1(cto)-1(r)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 127.68699646 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 130.06100464 12.82499981 Tm [(protein)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 161.44299316 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 163.81700134 12.82499981 Tm [(2;)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 171.94799805 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 174.32200623 12.82499981 Tm [(CEP2;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 198.60299683 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 200.977005 12.82499981 Tm [(BORG1)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 231.28799438 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001C000D>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CDC)-1(4)1(2E)-1(P)1(2)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 107.1740036 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0022>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 86 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 87 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 88 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 89 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 172.0249939 0.75 l 172.0249939 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 173.0249939 -0.25 l 173.0249939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 91 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 172.7749939 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 172.7749939 156.75 l h f* Q q 1 0 0 1 172.3999939 0 cm -0.625 -0.25 m 251.0249939 -0.25 l 251.0249939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 92 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CDC42,)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 31.61899948 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 36.11899948 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 41.09400177 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 45.59400177 11.72200012 Tm [(small)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 67.95800018 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 72.45800018 11.72200012 Tm [(Rho)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 89.59700012 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 94.09700012 11.72200012 Tm [(GTPa)1(se)-1(,)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 127.8690033 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 132.3690033 11.72200012 Tm [(regulat)1(e)-1(s)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 172.21000671 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 176.71000671 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 190.71099854 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 195.21099854 11.72200012 Tm [(fo)1(rmatio)1(n)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 237.91299438 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 8.84200001 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 13.34200001 27.3220005 Tm [(F-actin-conta)1(in)-1(ing)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 92.43900299 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 96.93900299 27.3220005 Tm [(st)1(ruc)-1(tures)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 139.56199646 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 144.06199646 27.3220005 Tm [(th)1(rough)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 178.95899963 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 183.45899963 27.3220005 Tm [(its)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 193.3730011 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 197.8730011 27.3220005 Tm [(interactio)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(n)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 5.546 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 10.04599953 42.92200089 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 28.44199944 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 32.94200134 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 46.94300079 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 51.44300079 42.92200089 Tm [(do)1(wnstr)1(e)-1(am)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 105.04299927 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 109.54299927 42.92200089 Tm [(effec)-1(t)1(or)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 143.02099609 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 147.52099609 42.92200089 Tm [(pro)1(tein)-1(s)1(.)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 185.16000366 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 189.66000366 42.92200089 Tm [(The)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 205.46699524 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 209.96699524 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 241.27400208 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 37.50699997 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 42.00699997 58.52199936 Tm [(by)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 52.51900101 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 57.01900101 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 72.47499847 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 76.97499847 58.52199936 Tm [(gene)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 98.49099731 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 102.99099731 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 109.55200195 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 114.05200195 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 119.02700043 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 123.52700043 58.52199936 Tm [(member)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 159.79100037 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 164.29100037 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 173.13299561 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 177.63299561 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 191.63400269 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 196.13400269 58.52199936 Tm [(Borg)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 216.69599915 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 221.19599915 58.52199936 Tm [(fa)1(mi)-1(l)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(y)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 4.76399994 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 9.26399994 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 18.1060009 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 22.6060009 74.12200165 Tm [(CDC42)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 52.05799866 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 56.55799866 74.12200165 Tm [(effec)-1(t)1(or)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 90.03600311 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 94.53600311 74.12200165 Tm [(pro)1(tein)-1(s)1(.)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 132.17500305 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 136.67500305 74.12200165 Tm [(Borg)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 157.23699951 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 161.73699951 74.12200165 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 187.81900024 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 192.31900024 74.12200165 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 227.79200745 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 232.29200745 74.12200165 Tm [(co)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ntain)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 21.81399918 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 26.31399918 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 31.28899956 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 35.78900146 89.72200012 Tm [(CRIB)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 55.97700119 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 60.47700119 89.72200012 Tm [(\(Cdc42)-1(/Rac)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 109.53800201 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 114.03800201 89.72200012 Tm [(interactive-binding)1(\))] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 198.98399353 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 203.48399353 89.72200012 Tm [(do)1(main.)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 238.47799683 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(They)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 20.57099915 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 25.07099915 105.3219986 Tm [(bind)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 44.51699829 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 49.01699829 105.3219986 Tm [(to)1(,)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 60.25799942 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 64.75800323 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 81.03500366 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 85.53500366 105.3219986 Tm [(ne)-1(g)1(atively)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 129.65600586 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 134.15600586 105.3219986 Tm [(regulat)1(e)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 169.83099365 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 174.33099365 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 188.33200073 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 192.83200073 105.3219986 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 228.57299805 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 233.07299805 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 241.91499329 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(CDC42.)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 31.61899948 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 36.11899948 120.92199707 Tm [(Coexpr)1(e)-1(ssio)1(n)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 93.81500244 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 98.31500244 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 107.15699768 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 111.65699768 120.92199707 Tm [(th)1(is)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 127.11299896 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 131.61300659 120.92199707 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 162.91999817 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 167.41999817 120.92199707 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 185.81599426 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 190.31599426 120.92199707 Tm [(CDC42)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 219.76800537 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 224.26800537 120.92199707 Tm [(sug)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(gest)1(e)-1(d)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 29.24600029 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 33.74599838 136.52200317 Tm [(a)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 38.72100067 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 43.22100067 136.52200317 Tm [(role)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 59.88100052 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 64.3809967 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 73.22299957 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 77.72299957 136.52200317 Tm [(th)1(is)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 93.17900085 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 97.67900085 136.52200317 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 128.98599243 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 133.48599243 136.52200317 Tm [(in)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 141.42700195 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 145.92700195 136.52200317 Tm [(actin)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 166.70899963 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 171.20899963 136.52200317 Tm [(filament)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 206.53199768 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 211.03199768 136.52200317 Tm [(assem)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(bly)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 12.90699959 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 17.40699959 152.12199402 Tm [(and)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 33.68399811 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 38.18399811 152.12199402 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 52.59400177 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 57.09400177 152.12199402 Tm [(sha)1(pe)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 82.6309967 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 87.1309967 152.12199402 Tm [(control.)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 119.98500061 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q /GS2 gs 1 g 0.375 0.75 m 172.0249939 0.75 l 172.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 173.0249939 -0.25 l 173.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 247 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 248 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 172.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 172.7749939 16.35000038 l h f* Q q 1 0 0 1 172.3999939 0 cm -0.625 -0.25 m 251.0249939 -0.25 l 251.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 249 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 46.03300095 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 172.3999939 0.75 m 172.3999939 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 172.3999939 157.5 m 172.3999939 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 173.4750061 m 423.17498779 173.4750061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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