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[<0009000A000B000C>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 60.56000137 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84.18499756 12.82499981 Tm [(DUSP9)] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 115.57700348 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 168.07699585 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 173.32699585 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000D000A000B000C>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(DU)1(S)-1(P9)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 112.50099945 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 114.875 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 140.5249939 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 142.89900208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 186.45799255 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 188.83200073 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 226.62800598 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 26 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B>] TJ ET EMC /P <</MCID 27 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(MKP)1(4;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 90.98799896 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 93.36199951 12.82499981 Tm [(MKP)1(-4)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 121.75499725 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000F>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(DUSP9)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 91.76699829 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0011>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001200130014>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00150016>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0018>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0019001A001B001C>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001D001E001F000E>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00200004>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0021>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0022>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00060007001F0024>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 84 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 85 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 423.39001465 cm /P <</MCID 87 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 12.89099979 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 451.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 147.2749939 0.75 l 147.2749939 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 148.2749939 -0.25 l 148.2749939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 88 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 148.0249939 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 148.0249939 156.75 l h f* Q q 1 0 0 1 147.6499939 0 cm -0.625 -0.25 m 275.7749939 -0.25 l 275.7749939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 247.7480011 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 252.2480011 11.72200012 Tm [(du)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(al)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 7.36999989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 11.86999989 27.3220005 Tm [(speci)-1(f)1(ic)-1(it)1(y)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 54.3390007 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 58.8390007 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 90.14600372 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 94.64600372 27.3220005 Tm [(ph)1(osph)1(ata)1(se)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 149.68800354 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 154.18800354 27.3220005 Tm [(subf)1(amily)-1(.)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 197.89599609 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 202.39599609 27.3220005 Tm [(These)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 227.47599792 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 231.97599792 27.3220005 Tm [(ph)1(osph)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(at)1(ases)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 26.74099922 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 31.24099922 42.92200089 Tm [(inac)-1(t)1(ivat)1(e)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 72.5759964 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 77.0759964 42.92200089 Tm [(th)1(e)-1(ir)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 96.90899658 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 101.40899658 42.92200089 Tm [(ta)1(rget)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 127.38899994 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 131.88900757 42.92200089 Tm [(ki)-1(na)1(se)-1(s)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 163.14300537 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 167.64300537 42.92200089 Tm [(by)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 178.15499878 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 182.65499878 42.92200089 Tm [(deph)1(osph)1(orylating)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 264.32699585 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(bo)1(th)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 20.36400032 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 24.86400032 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 38.86500168 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 43.36500168 58.52199936 Tm [(ph)1(osph)1(oserin)-1(e/thr)1(e)-1(o)1(n)-1(ine)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 152.90699768 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 157.40699768 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 173.68400574 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 178.18400574 58.52199936 Tm [(ph)1(osph)1(otyros)1(i)-1(ne)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 250.86099243 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 255.36099243 58.52199936 Tm [(re)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(sidues.)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 29.3029995 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 33.8030014 74.12200165 Tm [(They)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 54.37400055 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 58.87400055 74.12200165 Tm [(ne)-1(g)1(atively)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 102.99500275 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 107.49500275 74.12200165 Tm [(regulat)1(e)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 143.16999817 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 147.66999817 74.12200165 Tm [(members)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 188.1000061 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 192.6000061 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 201.44200134 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 205.94200134 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 219.94299316 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 224.44299316 74.12200165 Tm [(mito)1(gen)-1(-)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(activat)1(ed)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 39.15100098 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 43.65100098 89.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 74.95800018 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 79.45800018 89.72200012 Tm [(\(MAP)1(\))] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 106.10199738 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 110.60199738 89.72200012 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 137.69000244 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 142.19000244 89.72200012 Tm [(superfa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 192.27400208 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 196.77400208 89.72200012 Tm [(\(MAP)1(K/ERK,)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 248.67300415 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 253.17300415 89.72200012 Tm [(SA)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(PK/JNK,)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 33.82500076 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 38.32500076 105.3219986 Tm [(p38)-1(\),)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 59.80099869 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 64.3010025 105.3219986 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 89.39800262 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 93.89800262 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 100.45899963 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 104.95899963 105.3219986 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 150.08599854 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 154.58599854 105.3219986 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 172.98199463 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 177.48199463 105.3219986 Tm [(ce)-1(llular)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 208.2440033 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 212.7440033 105.3219986 Tm [(pro)1(life)-1(r)1(ation)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 266.09399414 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 16.27700043 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 20.77700043 120.92199707 Tm [(dif)1(fe)-1(r)1(e)-1(nt)1(i)-1(a)1(tion.)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 84.26899719 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 88.76899719 120.92199707 Tm [(Diff)1(e)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 126.80799866 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 131.30799866 120.92199707 Tm [(members)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 171.73800659 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 176.23800659 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 185.08000183 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 189.58000183 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 203.58099365 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 208.08099365 120.92199707 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 234.16299438 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 238.66299438 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 247.50500488 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 252.00500488 120.92199707 Tm [(du)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(al)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 7.36999989 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 11.86999989 136.52200317 Tm [(speci)-1(f)1(ic)-1(it)1(y)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 54.3390007 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 58.8390007 136.52200317 Tm [(ph)1(osph)1(ata)1(se)-1(s)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 118.04699707 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 122.54699707 136.52200317 Tm [(sho)1(w)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 145.08200073 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 149.58200073 136.52200317 Tm [(dist)1(in)-1(ct)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 181.05999756 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 185.55999756 136.52200317 Tm [(subst)1(rat)1(e)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 225.41000366 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 229.91000366 136.52200317 Tm [(speci)-1(f)1(ic)-1(it)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ies)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 11.66699982 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 16.16699982 152.12199402 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 28.44499969 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 32.94499969 152.12199402 Tm [(var)1(i)-1(o)1(u)-1(s)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 63.9090004 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 68.40899658 152.12199402 Tm [(MAP)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 89.04100037 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 93.54100037 152.12199402 Tm [(ki)-1(na)1(se)-1(s,)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 126.96099854 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 131.46099854 152.12199402 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 168.40100098 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 172.90100098 152.12199402 Tm [(tiss)1(u)-1(e)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 197.63299561 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 202.13299561 152.12199402 Tm [(dist)1(ributio)1(n)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 251.94500732 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 256.44500732 152.12199402 Tm [(an)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 147.6499939 0.75 m 147.6499939 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 157.125 m 423.17498779 157.125 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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