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0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(CDC)-1(2)1(5C)-1(\(P)1(h)-1(osp)-1(ho-S)-1(e)1(r198\))] TJ ET EMC /P <</MCID 8 >> BDC BT 1 0 0 -1 186.43699646 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 191.68699646 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 244.18699646 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 249.43699646 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CDC25C\(Pho)-1(sph)-1(o-S)-1(e)1(r19)1(8\))] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 194.04499817 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 196.41900635 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 222.06900024 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 224.44299316 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 268.00201416 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 270.37600708 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 308.17199707 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CDC)-1(2)1(5;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 94.11000061 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 96.48400116 12.82499981 Tm [(PP)1(P1R6)1(0)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 134.42300415 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 32 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 33 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001D>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001E000D>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001F000D>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CDC)-1(2)1(5C)-1(\(P)1(h)-1(osp)-1(ho-S)-1(e)1(r198\))] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 173.31199646 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0020002100220023000D>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002400250026000D>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120027000D>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 71 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 163.7749939 0.75 l 163.7749939 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 164.7749939 -0.25 l 164.7749939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 75 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.5249939 0.75 m 422.375 0.75 l 422.375 156.75 l 164.5249939 156.75 l h f* Q q 1 0 0 1 164.1499939 0 cm -0.625 -0.25 m 259.2250061 -0.25 l 259.2250061 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 77 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 54.3390007 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 58.8390007 11.72200012 Tm [(hig)1(hly)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 85.23300171 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 89.73300171 11.72200012 Tm [(conse)-1(rv)1(e)-1(d)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 133.80999756 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 138.30999756 11.72200012 Tm [(during)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 166.74699402 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 171.24699402 11.72200012 Tm [(evolution)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 211.7559967 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 216.2559967 11.72200012 Tm [(and)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 232.53300476 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 237.03300476 11.72200012 Tm [(it)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 242.78100586 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(plays)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 22.04700089 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 26.54700089 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 31.52199936 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 36.02199936 27.3220005 Tm [(ke)-1(y)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 50.79199982 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 55.29199982 27.3220005 Tm [(role)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 71.95200348 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 76.45200348 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 84.39299774 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 88.89299774 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 102.89399719 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 107.39399719 27.3220005 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 151.625 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 156.125 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 164.96699524 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 169.46699524 27.3220005 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 183.8769989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 188.3769989 27.3220005 Tm [(division.)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 223.64300537 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 228.14300537 27.3220005 Tm [(The)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 243.94999695 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 37.50699997 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 42.00699997 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 73.31400299 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 77.81400299 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 84.375 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 88.875 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 93.84999847 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 98.34999847 42.92200089 Tm [(tyro)1(sin)-1(e)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 132.83799744 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 137.33799744 42.92200089 Tm [(ph)1(osph)1(ata)1(se)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 192.38000488 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 196.88000488 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 213.15699768 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 217.65699768 42.92200089 Tm [(belong)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(s)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 4.16599989 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 8.66600037 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 17.74099922 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 22.24099922 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 36.24200058 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 40.74200058 58.52199936 Tm [(Cdc25)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 67.58799744 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 72.08799744 58.52199936 Tm [(ph)1(osph)1(ata)1(se)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 127.12999725 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 131.63000488 58.52199936 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 159.87800598 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 164.37800598 58.52199936 Tm [(It)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 170.3769989 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 174.8769989 58.52199936 Tm [(directs)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 203.60400391 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 208.10400391 58.52199936 Tm [(deph)1(osp)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ho)1(ry)-1(la)1(tion)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 43.84899902 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 48.34899902 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 57.19100189 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 61.69100189 74.12200165 Tm [(cy)-1(clin)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 85.81700134 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 90.31700134 74.12200165 Tm [(B-bo)1(u)-1(nd)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 128.17599487 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 132.67599487 74.12200165 Tm [(CDC2)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 156.8500061 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 161.3500061 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 177.6269989 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 182.1269989 74.12200165 Tm [(tr)1(i)-1(g)1(gers)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 215.53399658 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 220.03399658 74.12200165 Tm [(en)-1(t)1(ry)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 242.24000549 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 246.74000549 74.12200165 Tm [(i)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(nto)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 14.62100029 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 19.12100029 89.72200012 Tm [(mito)1(sis.)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 51.91699982 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 56.41699982 89.72200012 Tm [(It)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 62.41600037 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 66.91600037 89.72200012 Tm [(is)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 73.47699738 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 77.97699738 89.72200012 Tm [(also)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 95.23400116 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 99.73400116 89.72200012 Tm [(th)1(ought)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 134.54699707 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 139.04699707 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 148.12199402 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 152.62199402 89.72200012 Tm [(supp)1(re)-1(ss)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 190.70500183 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 195.20500183 89.72200012 Tm [(p53)-1(-)1(induc)-1(ed)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 250.02200317 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(gr)1(owt)1(h)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 30.91600037 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 35.41600037 105.3219986 Tm [(arr)1(e)-1(st)1(.)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 62.05599976 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 66.55599976 105.3219986 Tm [(Multiple)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 102.28800201 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 106.78800201 105.3219986 Tm [(alt)1(e)-1(rnat)1(ive)-1(ly)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 159.31100464 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 163.81100464 105.3219986 Tm [(splice)-1(d)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 193.89199829 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 198.39199829 105.3219986 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 239.31399536 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 243.81399536 105.3219986 Tm [(v)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(aria)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 28.84600067 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 33.34600067 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 42.18799973 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 46.68799973 120.92199707 Tm [(th)1(is)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 62.14400101 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 66.64399719 120.92199707 Tm [(gene)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 88.16000366 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 92.66000366 120.92199707 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 113.00700378 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 117.50700378 120.92199707 Tm [(been)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 139.01400757 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 143.51400757 120.92199707 Tm [(described,)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 187.66600037 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 192.16600037 120.92199707 Tm [(ho)1(weve)-1(r,)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 231.07499695 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 235.57499695 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 249.57600403 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(full-length)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 45.04800034 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 49.54800034 136.52200317 Tm [(nature)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 77.51000214 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 82.01000214 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 90.85199738 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 95.35199738 136.52200317 Tm [(many)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 119.06900024 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 123.56900024 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 132.41099548 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 136.91099548 136.52200317 Tm [(th)1(e)-1(m)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 159.34500122 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 163.84500122 136.52200317 Tm [(is)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 170.40600586 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 174.90600586 136.52200317 Tm [(not)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 189.5269928 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 194.0269928 136.52200317 Tm [(kn)-1(o)1(wn.)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 225.01300049 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 229.51300049 136.52200317 Tm [([pr)1(o)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(vided)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 23.73900032 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 28.23900032 152.12199402 Tm [(by)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 38.75099945 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 43.25099945 152.12199402 Tm [(RefSeq,)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 75.57700348 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 80.07700348 152.12199402 Tm [(Jul)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 91.58200073 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 96.08200073 152.12199402 Tm [(20)-1(08)-1(])] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 120.1989975 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q /GS2 gs 1 g 0.375 0.75 m 163.7749939 0.75 l 163.7749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 164.7749939 -0.25 l 164.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 244 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 245 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.5249939 0.75 m 422.375 0.75 l 422.375 16.35000038 l 164.5249939 16.35000038 l h f* Q q 1 0 0 1 164.1499939 0 cm -0.625 -0.25 m 259.2250061 -0.25 l 259.2250061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 246 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(IHC)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 15.62699986 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.1499939 0.75 m 164.1499939 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.1499939 157.5 m 164.1499939 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.75 0.75 m 422.75 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.125 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.375 157.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 173.4750061 m 423.125 173.4750061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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