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EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(ATIC)] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 82.43599701 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 87.68599701 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 171.68600464 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ATIC)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 82.43599701 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 84.80999756 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 118.01200104 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 120.38600159 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 180.36599731 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 182.74000549 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 217.21400452 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(5-amin)-1(oi)-1(m)1(i)-1(dazo)-1(le-4-car)1(b)-1(oxamid)-1(e)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 206.53900146 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 231.03399658 12.82499981 Tm [(rib)-1(onu)-1(c)1(l)-1(eotid)-1(e)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 293.47000122 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 317.96499634 12.82499981 Tm [(fo)-1(r)1(myltransferase)1(/IMP)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 415.29998779 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 0 30.49699783 Tm [(cy)1(cl)-1(oh)-1(y)1(d)-1(r)1(o)-1(lase;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 66.14299774 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 68.51699829 30.49699783 Tm [(PU)1(RH;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 95.73100281 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 98.10500336 30.49699783 Tm [(AICA)1(R;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 127.01100159 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 129.38499451 30.49699783 Tm [(AICA)1(RF)-1(T;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 168.23199463 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 170.60600281 30.49699783 Tm [(IMPCHA)1(S)-1(E;)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 218.63000488 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 221.0039978 30.49699783 Tm [(HEL)-1(-S-)-1(7)1(0p)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 264.50100708 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 260.37298584 cm /P <</MCID 57 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 288.31201172 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 58 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(C)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 124.30999756 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 126.34500122 12.04500008 Tm [(ter)1(min)-1(al)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 157.33500671 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 159.36999512 12.04500008 Tm [(200)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 173.05499268 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 175.08999634 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 198.1309967 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 200.16600037 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 218.59700012 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 220.63200378 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 228.125 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 230.16000366 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 255.84599304 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 257.88101196 12.04500008 Tm [(ATIC)] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAABB 9 Tf 1 0 0 -1 274.54098511 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 317.25100708 cm /P <</MCID 82 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 345.19000244 cm /P <</Lang (zh-CN) /MCID 83 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 373.1289978 cm /P <</MCID 85 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 401.06799316 cm q /GS2 gs 1 g 0.375 0.75 m 141.9750061 0.75 l 141.9750061 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 142.9750061 -0.25 l 142.9750061 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 86 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 16.18099976 19.52199936 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 20.68099976 19.52199936 Tm [(name:)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7250061 0.75 m 426.17501831 0.75 l 426.17501831 31.95000076 l 142.7250061 31.95000076 l h f* Q q 1 0 0 1 142.3500061 0 cm -0.625 -0.25 m 284.82501221 -0.25 l 284.82501221 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(5-aminoimida)1(zole-4-c)-1(a)1(rbox)1(amide)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 146.53100586 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 151.03100586 11.72200012 Tm [(ribo)1(n)-1(ucle)-1(o)1(tide)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 213.77200317 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 218.27200317 11.72200012 Tm [(fo)1(rmy)-1(lt)1(ransfe)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ras)1(e)-1(/IMP)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 38.47399902 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 42.97399902 27.3220005 Tm [(cy)-1(clohydro)1(lase)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 106.74299622 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 31.95000076 cm q /GS2 gs 1 g 0.375 0.75 m 141.9750061 0.75 l 141.9750061 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 142.9750061 -0.25 l 142.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 99 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 100 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7250061 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 142.7250061 16.35000038 l h f* Q q 1 0 0 1 142.3500061 0 cm -0.625 -0.25 m 284.82501221 -0.25 l 284.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 101 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(PU)1(RH)-1(;)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 27.22900009 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 31.72900009 11.72200012 Tm [(AICA)1(R;)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 61.10200119 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 65.60199738 11.72200012 Tm [(AICA)1(RFT;)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 104.91500092 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 109.41500092 11.72200012 Tm [(IMPCHASE;)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 157.98300171 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 162.48300171 11.72200012 Tm [(HEL-S-70)-1(p)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 208.29600525 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 48.29999924 cm q /GS2 gs 1 g 0.375 0.75 m 141.9750061 0.75 l 141.9750061 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 142.9750061 -0.25 l 142.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 111 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 112 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7250061 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 142.7250061 16.35000038 l h f* Q q 1 0 0 1 142.3500061 0 cm -0.625 -0.25 m 284.82501221 -0.25 l 284.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 113 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P31)-1(93)-1(9)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 64.65000153 cm q /GS2 gs 1 g 0.375 0.75 m 141.9750061 0.75 l 141.9750061 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 142.9750061 -0.25 l 142.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 115 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 118 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7250061 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 142.7250061 16.35000038 l h f* Q q 1 0 0 1 142.3500061 0 cm -0.625 -0.25 m 284.82501221 -0.25 l 284.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 119 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(08)-1(87)-1(9)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81 cm q /GS2 gs 1 g 0.375 0.75 m 141.9750061 0.75 l 141.9750061 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 142.9750061 -0.25 l 142.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 121 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 122 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7250061 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 142.7250061 16.35000038 l h f* Q q 1 0 0 1 142.3500061 0 cm -0.625 -0.25 m 284.82501221 -0.25 l 284.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 123 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 97.34999847 cm q /GS2 gs 1 g 0.375 0.75 m 141.9750061 0.75 l 141.9750061 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 142.9750061 -0.25 l 142.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 139 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 142 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7250061 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 142.7250061 16.35000038 l h f* Q q 1 0 0 1 142.3500061 0 cm -0.625 -0.25 m 284.82501221 -0.25 l 284.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 143 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 113.69999695 cm q /GS2 gs 1 g 0.375 0.75 m 141.9750061 0.75 l 141.9750061 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 142.9750061 -0.25 l 142.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 147 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 148 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7250061 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 142.7250061 16.35000038 l h f* Q q 1 0 0 1 142.3500061 0 cm -0.625 -0.25 m 284.82501221 -0.25 l 284.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 149 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 130.05000305 cm q /GS2 gs 1 g 0.375 0.75 m 141.9750061 0.75 l 141.9750061 78.75 l 0.375 78.75 l h f* Q q -0.625 -0.25 m 142.9750061 -0.25 l 142.9750061 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 161 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 42.92200089 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 162 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 142.7250061 0.75 m 426.17501831 0.75 l 426.17501831 78.75 l 142.7250061 78.75 l h f* Q q 1 0 0 1 142.3500061 0 cm -0.625 -0.25 m 284.82501221 -0.25 l 284.82501221 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 163 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(bif)1(u)-1(nctional)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 148.92300415 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 153.42300415 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 184.72999573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 189.22999573 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 206.45199585 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 210.95199585 11.72200012 Tm [(cata)1(l)-1(yzes)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 249.62399292 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 254.12399292 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 268.125 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 272.625 11.72200012 Tm [(l)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ast)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 12.49400043 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 16.99399948 27.3220005 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 33.17499924 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 37.67499924 27.3220005 Tm [(st)1(e)-1(ps)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 60.21500015 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 64.71499634 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 73.55699921 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 78.05699921 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 92.05799866 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 96.55799866 27.3220005 Tm [(de)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 107.42099762 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 111.92099762 27.3220005 Tm [(novo)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 133.63400269 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 138.13400269 27.3220005 Tm [(purine)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 165.91200256 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 170.41200256 27.3220005 Tm [(bios)1(y)-1(nt)1(he)-1(t)1(ic)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 223.01499939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 227.51499939 27.3220005 Tm [(pa)1(thw)1(ay.)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 266.14300537 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 270.64300537 27.3220005 Tm [(T)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(he)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 10.64799976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 15.14799976 42.92200089 Tm [(N-t)1(e)-1(r)1(mi)-1(na)1(l)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 61.9980011 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 66.4980011 42.92200089 Tm [(do)1(main)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 99.32499695 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 103.82499695 42.92200089 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 118.50700378 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 123.00700378 42.92200089 Tm [(ph)1(osph)1(oribos)1(y)-1(laminoimida)1(zolec)-1(a)1(r)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(bo)1(xamide)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 42.6969986 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 47.1969986 58.52199936 Tm [(fo)1(rmy)-1(lt)1(ransferas)1(e)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 122.45300293 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 126.95300293 58.52199936 Tm [(activit)1(y)-1(,)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 159.59100342 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 164.09100342 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 180.36799622 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 184.86799622 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 198.8690033 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 203.3690033 58.52199936 Tm [(C-t)1(e)-1(r)1(min)-1(a)1(l)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 248.92300415 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 253.42300415 58.52199936 Tm [(do)1(m)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ain)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 12.91600037 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 17.41600037 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 32.09799957 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 36.59799957 74.12200165 Tm [(IMP)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 53.54299927 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 58.04299927 74.12200165 Tm [(cy)-1(clohydro)1(lase)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 121.81199646 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 126.31199646 74.12200165 Tm [(activit)1(y)-1(.)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 158.94999695 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 163.44999695 74.12200165 Tm [(A)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 169.78300476 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 174.28300476 74.12200165 Tm [(mutat)1(ion)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 213.60499573 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 218.10499573 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 226.04600525 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 230.54600525 74.12200165 Tm [(th)1(is)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 246.0019989 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 250.5019989 74.12200165 Tm [(gene)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 272.01800537 74.12200165 Tm [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 208.80000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3500061 0.75 m 142.3500061 31.95000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3500061 32.70000076 m 142.3500061 48.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3500061 49.05000305 m 142.3500061 64.65000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3500061 65.40000153 m 142.3500061 81 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3500061 81.75 m 142.3500061 97.34999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3500061 98.09999847 m 142.3500061 113.69999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3500061 114.44999695 m 142.3500061 130.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.3500061 130.80000305 m 142.3500061 208.80000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.55001831 0.75 m 426.55001831 208.80000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92501831 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 32.32500076 m 426.17501831 32.32500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 48.67500305 m 426.17501831 48.67500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.02500153 m 426.17501831 65.02500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 81.375 m 426.17501831 81.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 97.72499847 m 426.17501831 97.72499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.07499695 m 426.17501831 114.07499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 130.42500305 m 426.17501831 130.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 209.17500305 m 426.92501831 209.17500305 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
endobj
6 0 obj
<</Length1 106 0 R/Length 29796>>stream
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