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<> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 101.45200348 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 153.95199585 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.45199585 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CD63)] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.43599701 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.80999756 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.46000671 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.83399963 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.39300537 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.76699829 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.56300354 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CD63)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.70200348 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.0759964 12.82499981 Tm [(mol)-1(e)1(cul)-1(e;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.03500366 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.40899658 12.82499981 Tm [(MLA1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.00700378 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.3809967 12.82499981 Tm [(ME491;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.25999451 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.63400269 12.82499981 Tm [(LAMP-3;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.8710022 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.24499512 12.82499981 Tm [(OMA81)1(H;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.24499512 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 280.61898804 12.82499981 Tm [(TS)-1(P)1(AN3)1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 319.48098755 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CD63)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.70200348 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002200230024000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 154.7749939 0.75 l 154.7749939 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 155.7749939 -0.25 l 155.7749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 155.5249939 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 155.5249939 172.3500061 l h f* Q q 1 0 0 1 155.1499939 0 cm -0.625 -0.25 m 268.2749939 -0.25 l 268.2749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.7480011 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.2480011 11.72200012 Tm [(tr)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ansmembra)1(n)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.47100067 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.97100067 27.3220005 Tm [(4)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.24900055 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.74900055 27.3220005 Tm [(superfa)1(mi)-1(ly,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.5 27.3220005 Tm [(also)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.75700378 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.25700378 27.3220005 Tm [(kn)-1(o)1(wn)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.07600403 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.57600403 27.3220005 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.71699524 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.21699524 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.21800232 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.71800232 27.3220005 Tm [(tetr)1(aspa)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(nin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.48700047 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.98699951 42.92200089 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.23500061 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.73500061 42.92200089 Tm [(Most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.76899719 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.26899719 42.92200089 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.11100006 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.61100006 42.92200089 Tm [(th)1(e)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.88400269 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.38400269 42.92200089 Tm [(members)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.81399536 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.31399536 42.92200089 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.83200073 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.33200073 42.92200089 Tm [(ce)-1(ll-surf)1(ac)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.4980011 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.9980011 42.92200089 Tm [(pro)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ins)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.10700035 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.60700035 58.52199936 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.82899857 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.32899857 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.84700012 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.34700012 58.52199936 Tm [(chara)1(c)-1(terized)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.87999725 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.37999725 58.52199936 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.89199829 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.39199829 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.39300537 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.89300537 58.52199936 Tm [(presenc)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.62199402 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.12199402 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.96400452 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.46400452 58.52199936 Tm [(fo)1(u)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.28799438 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.78799438 58.52199936 Tm [(hydro)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ph)1(obic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.66699982 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.16699982 74.12200165 Tm [(do)1(mains.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.32700348 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.82700348 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.63400269 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.13400269 74.12200165 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.60699463 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.10699463 74.12200165 Tm [(mediat)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.23199463 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.73199463 74.12200165 Tm [(signal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.96499634 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.46499634 74.12200165 Tm [(tr)1(ansduc)-1(t)1(io)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.546 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.04599953 89.72200012 Tm [(eve)-1(nt)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.04800034 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.54800034 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.77000046 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.26999664 89.72200012 Tm [(play)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.15100098 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.65100098 89.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.62599945 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.12599945 89.72200012 Tm [(role)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.78600311 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.28600311 89.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.22699738 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.727005 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.72799683 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.22799683 89.72200012 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.45899963 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.95899963 89.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.80099487 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.30099487 89.72200012 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.71099854 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.21099854 89.72200012 Tm [(develo)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(pment,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.35300064 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.85300064 105.3219986 Tm [(activat)1(ion,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.97000122 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.47000122 105.3219986 Tm [(gr)1(owt)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.38600159 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.88600159 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.16299438 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.66299438 105.3219986 Tm [(mot)1(il)-1(it)1(y)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.63900757 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.13900757 105.3219986 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.94599915 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.44599915 105.3219986 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.95300293 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.45300293 105.3219986 Tm [(pro)1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.04699993 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.54700089 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.1079998 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.6079998 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.58300018 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.08300018 120.92199707 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.49300003 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.99300003 120.92199707 Tm [(surfa)1(c)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.85600281 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.35600281 120.92199707 Tm [(glyc)-1(o)1(prot)1(ei)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.81300354 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.31300354 120.92199707 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.53500366 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.03500366 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.59599304 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.09599304 120.92199707 Tm [(kn)-1(o)1(wn)] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.91499329 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.41499329 120.92199707 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.49000549 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.99000549 120.92199707 Tm [(compl)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(ex)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.66800022 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.16800022 136.52200317 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.56399918 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.06399918 136.52200317 Tm [(integrins.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.93099976 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.43099976 136.52200317 Tm [(It)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.43000031 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.93000031 136.52200317 Tm [(may)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.10099792 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.60099792 136.52200317 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.34199524 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.84199524 136.52200317 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.98300171 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.48300171 136.52200317 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.45799255 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.95799255 136.52200317 Tm [(bloo)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.30099487 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.80099487 136.52200317 Tm [(plat)1(el)-1(et)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.23300171 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.73300171 136.52200317 Tm [(acti)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(vat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.7140007 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.2140007 152.12199402 Tm [(marker.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.66799927 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.16799927 152.12199402 Tm [(Deficie)-1(nc)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.48200226 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.98200226 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.8239975 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.32400513 152.12199402 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.77999878 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.27999878 152.12199402 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.58700562 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.08700562 152.12199402 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.647995 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.147995 152.12199402 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.2749939 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.7749939 152.12199402 Tm [(wit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.54199982 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.04199982 167.72200012 Tm [(He)-1(rma)1(n)-1(sky-Pudla)1(k)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.3010025 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.8010025 167.72200012 Tm [(syndrome.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.897995 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.397995 167.72200012 Tm [(Also)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.01300049 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.51300049 167.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.96899414 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.46899414 167.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.98500061 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.48500061 167.72200012 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.16700745 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.66700745 167.72200012 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.17399597 167.72200012 Tm [( )] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 155.1499939 0.75 m 155.1499939 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
endstream
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6 0 obj
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