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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 100.93499756 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 150.61099243 23.67700005 Tm 0 Tr [(CD)-1(59)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 203.92399597 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 314.36401367 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(CD59)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 111.95200348 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 164.45199585 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.70199585 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CD59)] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.43599701 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.80999756 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.46000671 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.83399963 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.39300537 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.76699829 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.56300354 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CD59)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.70200348 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.81900024 12.82499981 Tm [(mol)-1(e)1(cul)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.96800232 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.08500671 12.82499981 Tm [(\(CD)-1(5)1(9)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.97099304 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.08799744 12.82499981 Tm [(bl)-1(oo)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.60499573 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.72200012 12.82499981 Tm [(gr)1(o)-1(up\))-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.88900757 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.0059967 12.82499981 Tm [(1F5;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.28399658 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.40100098 12.82499981 Tm [(EJ16;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.32901001 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.4460144 12.82499981 Tm [(EJ30;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.37399292 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.49099731 12.82499981 Tm [(EL)-1(32)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 324.48498535 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 328.60198975 12.82499981 Tm [(G344)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 354.00100708 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 358.11801147 12.82499981 Tm [(MIN)1(1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 384.6499939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 388.76699829 12.82499981 Tm [(MIN)1(2;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 415.29901123 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 30.49699783 Tm [(MIN)1(3;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.53199959 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.90600014 30.49699783 Tm [(MIRL;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.45399857 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.82799911 30.49699783 Tm [(HRF20;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.34899902 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.72299957 30.49699783 Tm [(MACIF;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.65399933 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.02799988 30.49699783 Tm [(MEM43;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.56300354 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.93699646 30.49699783 Tm [(MIC11;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.61199951 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.98599243 30.49699783 Tm [(MSK21;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.69599915 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.07000732 30.49699783 Tm [(16.3A5)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.89300537 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.26699829 30.49699783 Tm [(HR)] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.51000977 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0015000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 265.97299194 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CD59)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.70200348 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 299.51199341 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 333.05099487 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0022>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 366.58999634 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 400.1289978 m 416.75 400.1289978 l 416.75 431.32901001 l -1.45000005 431.32901001 l h f* Q q 1 0 0 1 0 400.1289978 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 431.32901001 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 459.26800537 cm q /GS2 gs 1 g 0.375 0.75 m 164.17500305 0.75 l 164.17500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 165.17500305 -0.25 l 165.17500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.92500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 164.92500305 156.75 l h f* Q q 1 0 0 1 164.55000305 0 cm -0.625 -0.25 m 258.875 -0.25 l 258.875 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.08000183 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.58000183 11.72200012 Tm [(surfa)1(c)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.44299316 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.94299316 11.72200012 Tm [(glyc)-1(o)1(prot)1(ei)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.3999939 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.8999939 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.12199402 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.62199402 11.72200012 Tm [(reg)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ulates)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.54100037 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.04100037 27.3220005 Tm [(compleme)-1(nt-)1(me)-1(d)1(iated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.17300415 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.67300415 27.3220005 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.08299255 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.58299255 27.3220005 Tm [(lysis,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.63499451 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.13499451 27.3220005 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.41200256 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.91200256 27.3220005 Tm [(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.66000366 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.16000366 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.72099304 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.22099304 27.3220005 Tm [(involve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 42.92200089 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.19799995 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.69799995 42.92200089 Tm [(lymphocyte)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.03700256 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.53700256 42.92200089 Tm [(signal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.76999664 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.26999664 42.92200089 Tm [(tr)1(ansduc)-1(t)1(ion.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.7440033 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.2440033 42.92200089 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.5059967 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.0059967 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.31300354 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.81300354 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.37399292 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.87399292 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.84899902 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(po)1(ten)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.82799911 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.32799911 58.52199936 Tm [(inhibito)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.86000061 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.36000061 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.20200348 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.70200348 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.70300293 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.20300293 58.52199936 Tm [(compleme)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.55900574 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.05900574 58.52199936 Tm [(membrane)] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.84300232 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.34300232 58.52199936 Tm [(at)1(tack)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.41099548 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(complex,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.64599991 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.14599991 74.12200165 Tm [(wh)1(e)-1(r)1(e)-1(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.95500183 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.45500183 74.12200165 Tm [(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.20300293 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.70300293 74.12200165 Tm [(binds)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.31500244 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.81500244 74.12200165 Tm [(compleme)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.17100525 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.67100525 74.12200165 Tm [(C8)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.96899414 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.46899414 74.12200165 Tm [(and/or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.75 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.25 74.12200165 Tm [(C9)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.54800415 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(during)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.43700027 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.93700027 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.93799973 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.43799973 89.72200012 Tm [(assembly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.19100189 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.69100189 89.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.53299713 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.03299713 89.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.48899841 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.98899841 89.72200012 Tm [(complex,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.63499451 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.13499451 89.72200012 Tm [(th)1(e)-1(r)1(e)-1(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.19099426 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.69099426 89.72200012 Tm [(inhibitin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.25799942 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.75799942 105.3219986 Tm [(inc)-1(or)1(pora)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.26699829 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.76699829 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.60900116 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.10900116 105.3219986 Tm [(multiple)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.48100281 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.98100281 105.3219986 Tm [(copies)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.6309967 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.1309967 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.9730072 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.4730072 105.3219986 Tm [(C9)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.77099609 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.27099609 105.3219986 Tm [(into)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.28700256 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.78700256 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.78799438 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(complex,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.64599991 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.14599991 120.92199707 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.24299622 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.74299622 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.30400085 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.80400085 120.92199707 Tm [(ne)-1(cessary)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.58300018 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.08299255 120.92199707 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.36099243 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.86099243 120.92199707 Tm [(osmo)1(l)-1(yt)1(ic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.32299805 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.82299805 120.92199707 Tm [(po)1(re)] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.83599854 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.33599854 120.92199707 Tm [(fo)1(rmati)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(on.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.43400002 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.93400002 136.52200317 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.19599915 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.69599915 136.52200317 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.00299835 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.50299835 136.52200317 Tm [(also)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.76000214 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.26000214 136.52200317 Tm [(plays)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.30699921 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.80699921 136.52200317 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.78199768 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.28199768 136.52200317 Tm [(role)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.94200134 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.44200134 136.52200317 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.38299561 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.88299561 136.52200317 Tm [(signal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.11599731 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.61599731 136.52200317 Tm [(tr)1(ansduc)-1(t)1(io)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.546 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.04599953 152.12199402 Tm [(pa)1(thw)1(ays)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.67300034 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.17300034 152.12199402 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.11399841 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.61399841 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.61499786 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.11499786 152.12199402 Tm [(activat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.06500244 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.56500244 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.40699768 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.90699768 152.12199402 Tm [(T)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.06599426 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.56599426 152.12199402 Tm [(ce)-1(lls.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.30799866 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.80799866 152.12199402 Tm [(Mutat)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.65699768 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.15699768 152.12199402 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.0980072 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.5980072 152.12199402 Tm [(th)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.55000305 0.75 m 164.55000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 157.125 m 423.17498779 157.125 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
endstream
endobj
6 0 obj
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