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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 90.38600159 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 140.06199646 23.67700005 Tm 0 Tr [(BCL2A)1(1)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 214.4730072 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 324.91299438 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(BCL)-1(2)1(A1)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 111.19300079 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 163.69299316 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.44299316 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(BCL2A1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.17700195 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.5510025 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.20100403 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.57499695 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.13400269 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.50799561 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.30400085 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(GRS;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.95899963 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.33300018 12.82499981 Tm [(BFL)-1(1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.41500092 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.78900146 12.82499981 Tm [(ACC-1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.40800476 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.78199768 12.82499981 Tm [(ACC-2;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.40100098 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.7749939 12.82499981 Tm [(HBPA)1(1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.66000366 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.03399658 12.82499981 Tm [(BCL)-1(2)1(L)-1(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.81599426 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0010000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(BCL)-1(2)1(A1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.44300079 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0012000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0019000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B001C000F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001D0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002200230024000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00060007001C0025000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 147.67500305 0.75 l 147.67500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 148.67500305 -0.25 l 148.67500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 148.42500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 148.42500305 172.3500061 l h f* Q q 1 0 0 1 148.05000305 0 cm -0.625 -0.25 m 275.375 -0.25 l 275.375 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(BCL)-1(-)1(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.73500061 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.23500061 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.54200745 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.04200745 11.72200012 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.29000854 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 27.3220005 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.77999878 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.27999878 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.12200165 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.62200165 27.3220005 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.07800293 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.57800293 27.3220005 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.66000366 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.16000366 27.3220005 Tm [(fo)1(rm)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.8710022 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.3710022 27.3220005 Tm [(hetero-)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.52999878 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.02999878 27.3220005 Tm [(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.18800354 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.68800354 27.3220005 Tm [(ho)1(modimers)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.3999939 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.8999939 27.3220005 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.30300045 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80300045 42.92200089 Tm [(act)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.6439991 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.14400101 42.92200089 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.28499985 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.78499985 42.92200089 Tm [(anti-)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.9469986 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.4469986 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.72399902 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.22399902 42.92200089 Tm [(pro)1(-ap)1(opt)1(otic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.55200195 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.05200195 42.92200089 Tm [(regulat)1(ors)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.94500732 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.44500732 42.92200089 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.66700745 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.16700745 42.92200089 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.68499756 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.18499756 42.92200089 Tm [(invol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ved)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.58699989 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.08699989 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.02799988 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.52799988 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.50299835 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.00299835 58.52199936 Tm [(wid)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.36700058 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.86699677 58.52199936 Tm [(var)1(i)-1(ety)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.62000275 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.12000275 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.96199799 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.46199799 58.52199936 Tm [(ce)-1(llular)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.22399902 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.72399902 58.52199936 Tm [(activit)1(i)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.09899902 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.59899902 58.52199936 Tm [(suc)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.36599731 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.86599731 58.52199936 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.00700378 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.50700378 58.52199936 Tm [(embryo)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(nic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.45400047 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.95400047 74.12200165 Tm [(development,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.11799622 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.61799622 74.12200165 Tm [(ho)1(me)-1(os)1(tasis)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.36300659 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.86300659 74.12200165 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.13999939 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.63999939 74.12200165 Tm [(tumor)1(ige)-1(nesis.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.93400574 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.43400574 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.24099731 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.74099731 74.12200165 Tm [(pro)1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.04699993 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.54700089 89.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.05400085 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.55400085 89.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.06600189 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.56600189 89.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.02200317 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.52200317 89.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.03800201 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.53800201 89.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.09899902 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.59899902 89.72200012 Tm [(ab)1(l)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.82299805 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.32299805 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.397995 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.897995 89.72200012 Tm [(reduc)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.36300659 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.86300659 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.86399841 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.36399841 89.72200012 Tm [(rele)-1(a)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.65600586 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.15600586 89.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.99798584 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(pro)1(-ap)1(opt)1(otic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.32799911 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.82800293 105.3219986 Tm [(cy)-1(t)1(oc)-1(h)1(rome)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.93199921 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.43199921 105.3219986 Tm [(c)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.94499969 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.44500732 105.3219986 Tm [(fro)1(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.15600586 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.65600586 105.3219986 Tm [(mito)1(c)-1(ho)1(n)-1(d)1(ria)] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.44400024 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.94400024 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.22099304 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.72099304 105.3219986 Tm [(block)] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.99899292 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(caspa)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.64899826 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.14899826 120.92199707 Tm [(activat)1(ion.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.26599884 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.76599884 120.92199707 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.02799988 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.52799988 120.92199707 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.04400635 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.54400635 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.10499573 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.60499573 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.58000183 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.08000183 120.92199707 Tm [(direct)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.64100647 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.14100647 120.92199707 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.7250061 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.2250061 120.92199707 Tm [(ta)1(rge)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 3.35299993 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 7.85300016 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.69499969 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.19499969 136.52200317 Tm [(NF-kapp)1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.5320015 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.03199768 136.52200317 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.67900085 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.17900085 136.52200317 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.12000275 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.62000275 136.52200317 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.61700439 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.11700439 136.52200317 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.19200134 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.69200134 136.52200317 Tm [(inflammat)1(ory)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.23800659 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.73800659 136.52200317 Tm [(mediat)1(ors,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.2480011 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 259.74798584 136.52200317 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.30300045 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80300045 152.12199402 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.36400032 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.86400032 152.12199402 Tm [(up-)1(re)-1(g)1(u)-1(la)1(ted)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.48300171 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.98300171 152.12199402 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.49500275 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.99500275 152.12199402 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.93499756 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.43499756 152.12199402 Tm [(extra)1(c)-1(ellu)-1(la)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.6289978 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.1289978 152.12199402 Tm [(signals,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.69500732 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.19500732 152.12199402 Tm [(suc)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.96200562 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.46200562 152.12199402 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.16599989 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.66600037 167.72200012 Tm [(gr)1(anu)-1(lo)1(c)-1(yte-macrop)1(hag)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.8789978 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.3789978 167.72200012 Tm [(colony)-1(-)1(stimulat)1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.24699402 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.74699402 167.72200012 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.86599731 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.36599731 167.72200012 Tm [(\(GM-)1(C)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.05000305 0.75 m 148.05000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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