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[<0009000A000B000C000D>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(CUL4B)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 117.03299713 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 169.53300476 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 174.78300476 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CU)1(L)-1(4B)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 111.51599884 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 113.88999939 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 139.53999329 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 141.91400146 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 185.4730072 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 187.84700012 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 225.64300537 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(SF)-1(M2;)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 89.75800323 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 92.13200378 12.82499981 Tm [(MRXSC)-1(;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 125.49299622 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 127.86699677 12.82499981 Tm [(MRXHF)-1(2)1(;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 167.49299622 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 169.86700439 12.82499981 Tm [(MRXS15)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 205.46299744 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001C000D>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CUL4B)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 90.78299713 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0022>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 80 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 81 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 83 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 152.92500305 0.75 l 152.92500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 153.92500305 -0.25 l 153.92500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 84 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 153.67500305 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 153.67500305 141.1499939 l h f* Q q 1 0 0 1 153.30000305 0 cm -0.625 -0.25 m 270.125 -0.25 l 270.125 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 86 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 54.3390007 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 58.8390007 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 63.81399918 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 68.31400299 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 104.57800293 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 109.07800293 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 117.91999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 122.41999817 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 136.42100525 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 140.92100525 11.72200012 Tm [(cu)-1(llin)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 163.71099854 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 168.21099854 11.72200012 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 196.45899963 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 200.95899963 11.72200012 Tm [(The)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 216.76600647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 221.26600647 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 258.77301025 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 31.30699921 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 35.80699921 27.3220005 Tm [(fo)1(rms)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 60.68399811 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 65.18399811 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 70.15899658 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 74.65899658 27.3220005 Tm [(complex)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 111.13800049 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 115.63800049 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 132.86000061 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 137.36000061 27.3220005 Tm [(func)-1(t)1(ions)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 177.26699829 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 181.76699829 27.3220005 Tm [(as)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 190.90800476 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 195.40800476 27.3220005 Tm [(an)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 205.92900085 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 210.42900085 27.3220005 Tm [(E3)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 220.65499878 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 225.15499878 27.3220005 Tm [(ubiquiti)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(n)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 5.546 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 10.04599953 42.92200089 Tm [(ligase)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 34.84000015 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 39.34000015 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 55.61700058 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 60.11700058 42.92200089 Tm [(cata)1(l)-1(yzes)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 98.78900146 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 103.28900146 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 117.29000092 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 121.79000092 42.92200089 Tm [(po)1(l)-1(yubiq)1(u)-1(it)1(in)-1(a)1(tion)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 201.08900452 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 205.58900452 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 214.43099976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 218.93099976 42.92200089 Tm [(speci)-1(f)1(ic)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 250.88800049 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 255.38800049 42.92200089 Tm [(p)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(rot)1(e)-1(in)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 25.55900002 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 30.05900002 58.52199936 Tm [(subst)1(rat)1(e)-1(s)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 74.07499695 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 78.57499695 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 86.51599884 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 91.01599884 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 105.01699829 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 109.51699829 58.52199936 Tm [(ce)-1(ll.)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 126.09300232 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 130.59300232 58.52199936 Tm [(The)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 146.3999939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 150.8999939 58.52199936 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 182.20700073 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 186.70700073 58.52199936 Tm [(interacts)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 223.55099487 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 228.05099487 58.52199936 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 246.44700623 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 250.94700623 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 255.92199707 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ring)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 17.13400078 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 21.63400078 74.12200165 Tm [(finger)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 46.99499893 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 51.49499893 74.12200165 Tm [(pro)1(tein)-1(,)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 84.96800232 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 89.46800232 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 105.74500275 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 110.24500275 74.12200165 Tm [(is)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 116.80599976 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 121.30599976 74.12200165 Tm [(required)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 157.84700012 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 162.34700012 74.12200165 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 174.625 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 179.125 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 193.12600708 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 197.62600708 74.12200165 Tm [(pro)1(teolysis)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 244.59899902 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 249.09899902 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 257.94100952 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(seve)-1(r)1(al)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 29.9090004 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 34.4090004 89.72200012 Tm [(regulat)1(ors)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 78.30200195 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 82.80200195 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 91.64399719 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 96.14399719 89.72200012 Tm [(DNA)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 116.64900208 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 121.14900208 89.72200012 Tm [(replic)-1(a)1(tion)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 166.73300171 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 171.23300171 89.72200012 Tm [(inc)-1(luding)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 211.08299255 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 215.58299255 89.72200012 Tm [(chromat)1(in)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 259.49798584 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(lic)-1(ensin)-1(g)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 37.81900024 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 42.31900024 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 58.59600067 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 63.09600067 105.3219986 Tm [(DNA)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 83.60099792 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 88.10099792 105.3219986 Tm [(replic)-1(a)1(tion)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 133.68499756 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 138.18499756 105.3219986 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 163.30400085 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 167.80400085 105.3219986 Tm [(1)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 173.08200073 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 177.58200073 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 193.85899353 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 198.35899353 105.3219986 Tm [(cy)-1(clin)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 222.48500061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 226.98500061 105.3219986 Tm [(E.)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 234.1000061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 238.6000061 105.3219986 Tm [(Multi)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ple)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 13.25 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 17.75 120.92199707 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 58.67200089 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 63.17200089 120.92199707 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 96.74199677 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 101.24199677 120.92199707 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 141.58399963 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 146.08399963 120.92199707 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 183.02400208 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 187.52400208 120.92199707 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 224.68400574 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 229.18400574 120.92199707 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 249.53100586 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 254.03100586 120.92199707 Tm [(b)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(ee)-1(n)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 15.75899982 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 20.25900078 136.52200317 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 45.94900131 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 50.44900131 136.52200317 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 62.72700119 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 67.22699738 136.52200317 Tm [(th)1(is)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 82.68299866 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 87.18299866 136.52200317 Tm [(gene)-1(.)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 110.86499786 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 152.92500305 0.75 l 152.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 153.92500305 -0.25 l 153.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 242 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 243 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 153.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 153.67500305 16.35000038 l h f* Q q 1 0 0 1 153.30000305 0 cm -0.625 -0.25 m 270.125 -0.25 l 270.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 244 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 46.03300095 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 157.5 cm q /GS2 gs 1 g 0.375 0.75 m 152.92500305 0.75 l 152.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 153.92500305 -0.25 l 153.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 248 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 253 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 153.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 153.67500305 16.35000038 l h f* Q q 1 0 0 1 153.30000305 0 cm -0.625 -0.25 m 270.125 -0.25 l 270.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 254 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CUL4B)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 28.28300095 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 153.30000305 0.75 m 153.30000305 141.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 153.30000305 141.8999939 m 153.30000305 157.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 153.30000305 158.25 m 153.30000305 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 141.5249939 m 422.42498779 141.5249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.875 m 422.42498779 157.875 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 174.2250061 m 423.17498779 174.2250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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