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[<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(BCCIP)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 103.72899628 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 156.22900391 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 166.72900391 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(BCCIP)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 108.71199799 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 111.08599854 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 136.73599243 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 139.11000061 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 182.66900635 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 185.04299927 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 222.83900452 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(BRCA2)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 91.40799713 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 93.78199768 12.82499981 Tm [(and)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 109.84500122 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 112.21900177 12.82499981 Tm [(CDKN)1(1A)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 147.90800476 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 150.28199768 12.82499981 Tm [(in)-1(te)1(ractin)-1(g)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 196.46600342 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 198.83999634 12.82499981 Tm [(protein)-1(;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 233.03199768 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 235.40600586 12.82499981 Tm [(TOK1;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 261.06100464 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 263.43499756 12.82499981 Tm [(TOK-1)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 289.49499512 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001C000D>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(BCCIP)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 87.97899628 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 70 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002200230024000D>] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 81 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 82 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 84 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 170.17500305 0.75 l 170.17500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 171.17500305 -0.25 l 171.17500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 170.92500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 170.92500305 172.3500061 l h f* Q q 1 0 0 1 170.55000305 0 cm -0.625 -0.25 m 252.875 -0.25 l 252.875 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 87 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(pro)1(duc)-1(t)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 81.85299683 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 86.35299683 11.72200012 Tm [(wa)1(s)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 102.59999847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 107.09999847 11.72200012 Tm [(isolat)1(e)-1(d)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 140.96899414 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 145.46899414 11.72200012 Tm [(on)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 156.73699951 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 161.23699951 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 175.23800659 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 179.73800659 11.72200012 Tm [(ba)1(sis)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 201.18800354 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 205.68800354 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 214.52999878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 219.02999878 11.72200012 Tm [(its)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 228.94400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 233.44400024 11.72200012 Tm [(int)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(eraction)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 35.04600143 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 39.54600143 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 57.94200134 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 62.44200134 27.3220005 Tm [(BRCA2)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 91.59500122 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 96.09500122 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 112.37200165 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 116.87200165 27.3220005 Tm [(p21)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 133.17599487 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 137.67599487 27.3220005 Tm [(pro)1(tein)-1(s)1(.)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 175.31500244 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 179.81500244 27.3220005 Tm [(It)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 185.81399536 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 190.31399536 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 196.875 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 201.375 27.3220005 Tm [(an)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 211.89599609 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 216.39599609 27.3220005 Tm [(evolut)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ionarily)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 31.62700081 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 36.1269989 42.92200089 Tm [(conse)-1(rv)1(e)-1(d)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 80.20400238 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 84.70400238 42.92200089 Tm [(nuc)-1(lear)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 116.22200012 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 120.72200012 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 152.02900696 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 156.52900696 42.92200089 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 174.92500305 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 179.42500305 42.92200089 Tm [(multiple)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 214.79699707 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 219.29699707 42.92200089 Tm [(intera)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(cting)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 21.56399918 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 26.06399918 58.52199936 Tm [(do)1(mains.)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 65.22399902 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 69.72399902 58.52199936 Tm [(The)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 85.53099823 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 90.03099823 58.52199936 Tm [(N-t)1(e)-1(r)1(mi)-1(na)1(l)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 136.8809967 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 141.3809967 58.52199936 Tm [(ha)1(l)-1(f)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 157.41200256 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 161.91200256 58.52199936 Tm [(sha)1(re)-1(s)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 189.30299377 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 193.80299377 58.52199936 Tm [(mod)1(e)-1(ra)1(te)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 235.69200134 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ho)1(mology)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 44.05500031 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 48.55500031 74.12200165 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 66.9509964 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 71.4509964 74.12200165 Tm [(regions)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 103.57900238 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 108.07900238 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 116.92099762 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 121.42099762 74.12200165 Tm [(calmodulin)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 169.09700012 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 173.59700012 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 189.87399292 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 194.37399292 74.12200165 Tm [(M-calpa)1(in)-1(,)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 239.77400208 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(sugg)1(e)-1(st)1(in)-1(g)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 47.54899979 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 52.04899979 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 69.27100372 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 73.77100372 89.72200012 Tm [(it)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 79.51899719 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 84.01899719 89.72200012 Tm [(may)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 102.19000244 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 106.69000244 89.72200012 Tm [(also)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 123.9469986 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 128.44700623 89.72200012 Tm [(bind)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 147.89300537 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 152.39300537 89.72200012 Tm [(calc)-1(ium.)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 187.33000183 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 191.83000183 89.72200012 Tm [(Fun)-1(ctiona)1(l)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 236.60099792 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(st)1(u)-1(d)1(ie)-1(s)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 30.48900032 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 34.98899841 105.3219986 Tm [(indic)-1(a)1(te)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 69.02899933 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 73.52899933 105.3219986 Tm [(th)1(at)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 90.75099945 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 95.25099945 105.3219986 Tm [(th)1(is)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 110.70700073 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 115.20700073 105.3219986 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 146.51400757 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 151.01400757 105.3219986 Tm [(may)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 169.18499756 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 173.68499756 105.3219986 Tm [(be)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 184.53900146 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 189.03900146 105.3219986 Tm [(an)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 199.55999756 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 204.05999756 105.3219986 Tm [(impor)1(tan)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(t)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 3.35299993 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 7.85300016 120.92199707 Tm [(cofacto)1(r)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 43.20700073 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 47.70700073 120.92199707 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 59.98500061 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 64.48500061 120.92199707 Tm [(BRCA2)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 93.63800049 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 98.13800049 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 106.07900238 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 110.57900238 120.92199707 Tm [(tumor)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 137.06900024 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 141.56900024 120.92199707 Tm [(supp)1(re)-1(ss)1(i)-1(o)1(n)-1(,)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 195.48100281 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 199.98100281 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 216.25799561 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 220.75799561 120.92199707 Tm [(a)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 225.73300171 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 230.23300171 120.92199707 Tm [(mo)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(dulat)1(or)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 31.18400002 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 35.68399811 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 44.52600098 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 49.02600098 136.52200317 Tm [(CDK)1(2)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 72.89299774 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 77.39299774 136.52200317 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 104.48100281 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 108.98100281 136.52200317 Tm [(activit)1(y)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 139.45300293 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 143.95300293 136.52200317 Tm [(via)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 156.04699707 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 160.54699707 136.52200317 Tm [(p21)-1(.)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 179.01699829 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 183.51699829 136.52200317 Tm [(This)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 200.77900696 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 205.27900696 136.52200317 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 236.58599854 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 14.68200016 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 19.18199921 152.12199402 Tm [(also)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 36.43899918 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 40.93899918 152.12199402 Tm [(been)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 62.44599915 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 66.94599915 152.12199402 Tm [(implicated)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 112.01599884 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 116.51599884 152.12199402 Tm [(in)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 124.45700073 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 128.95700073 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 142.95799255 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 147.45799255 152.12199402 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 191.68899536 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 196.18899536 152.12199402 Tm [(of)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 205.03100586 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 209.53100586 152.12199402 Tm [(BRCA2)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 238.68400574 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(and)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 16.27700043 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 20.77700043 167.72200012 Tm [(RA)1(D5)-1(1)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 50.39599991 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 54.89599991 167.72200012 Tm [(nuc)-1(lear)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 86.41400146 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 90.91400146 167.72200012 Tm [(fo)1(c)-1(us)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 113.98100281 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 118.48100281 167.72200012 Tm [(fo)1(rmatio)1(n)-1(,)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 163.34899902 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 167.84899902 167.72200012 Tm [(do)1(u)-1(b)1(le)-1(-)1(stra)1(n)-1(d)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 229.24899292 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 233.74899292 167.72200012 Tm [(br)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 170.55000305 0.75 m 170.55000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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