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[<0009000A000B000C000D>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(BCAR1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 117.65799713 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 170.15800476 12.82499981 Tm [(   )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 185.90800476 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(BCA)1(R1)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 112.14199829 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 114.51599884 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 140.16600037 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 142.53999329 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 186.09899902 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 188.4730072 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 226.26899719 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CAS;)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 82.30799866 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 84.68199921 12.82499981 Tm [(CAS1;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 109.31199646 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 111.68599701 12.82499981 Tm [(CASS)-1(1;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 141.13999939 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 143.51400757 12.82499981 Tm [(CRKA)1(S)-1(;)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 173.97799683 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 176.352005 12.82499981 Tm [(P1)1(30Cas)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 212.477005 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001C000D>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(BCAR1)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 91.40799713 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0022>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 78 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 79 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 84 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 85 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 87 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 143.17500305 0.75 l 143.17500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 144.17500305 -0.25 l 144.17500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 88 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 143.92500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 143.92500305 172.3500061 l h f* Q q 1 0 0 1 143.55000305 0 cm -0.625 -0.25 m 279.875 -0.25 l 279.875 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BCAR1,)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 31.31999969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 35.81999969 11.72200012 Tm [(or)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 44.97800064 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 49.47800064 11.72200012 Tm [(CAS,)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 69.19200134 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 73.69200134 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 80.25299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 84.75299835 11.72200012 Tm [(an)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 95.27400208 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 99.77400208 11.72200012 Tm [(Src)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 112.91799927 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 117.41799927 11.72200012 Tm [(\(MIM)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 140.65600586 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 145.15600586 11.72200012 Tm [(19)-1(00)-1(90)-1(\))] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 179.82899475 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 184.32899475 11.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 210.41099548 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 214.91099548 11.72200012 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 241.99899292 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 246.49899292 11.72200012 Tm [(subst)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(rat)1(e)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 16.87100029 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 21.37100029 27.3220005 Tm [(involved)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 57.74000168 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 62.24000168 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 70.18099976 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 74.68099976 27.3220005 Tm [(var)1(i)-1(o)1(u)-1(s)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 105.64499664 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 110.14499664 27.3220005 Tm [(ce)-1(llular)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 140.90699768 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 145.40699768 27.3220005 Tm [(eve)-1(nt)1(s,)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 175.57499695 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 180.07499695 27.3220005 Tm [(inc)-1(luding)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 219.92500305 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 224.42500305 27.3220005 Tm [(migra)1(tion,)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 268.60299683 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(survival,)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 34.52799988 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 39.02799988 42.92200089 Tm [(tr)1(ansfor)1(m)-1(a)1(tion,)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 105.37200165 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 109.87200165 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 126.14900208 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 130.64900208 42.92200089 Tm [(invasion.)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 168.28399658 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 172.78399658 42.92200089 Tm [(The)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 188.59100342 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 193.09100342 42.92200089 Tm [(molec)-1(ular)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 235.61199951 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 240.11199951 42.92200089 Tm [(cl)-1(o)1(n)-1(in)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(g)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 5.75699997 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 10.25699997 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 19.09900093 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 23.59900093 58.52199936 Tm [(p13)-1(0)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 45.18099976 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 49.68099976 58.52199936 Tm [(Cas)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 64.84200287 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 69.34200287 58.52199936 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 84.02400208 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 88.52400208 58.52199936 Tm [(sho)1(wn)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 116.60500336 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 121.10500336 58.52199936 Tm [(it)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 126.85299683 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 131.35299683 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 140.42799377 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 144.92799377 58.52199936 Tm [(represen)-1(t)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 185.93299866 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 190.43299866 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 195.40800476 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 199.90800476 58.52199936 Tm [(novel)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 223.40100098 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 227.90100098 58.52199936 Tm [(SH)-1(3)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 245.33399963 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 249.83399963 58.52199936 Tm [(cont)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(aining)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 26.61300087 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 31.11300087 74.12200165 Tm [(signaling)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 70.04399872 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 74.54399872 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 113.76100159 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 118.26100159 74.12200165 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 136.65699768 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 141.15699768 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 146.13200378 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 150.63200378 74.12200165 Tm [(cl)-1(ust)1(e)-1(r)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 179.147995 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 183.647995 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 192.49000549 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 196.99000549 74.12200165 Tm [(multiple)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 232.36199951 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 236.86199951 74.12200165 Tm [(put)1(ativ)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(e)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 5.10599995 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 9.60599995 89.72200012 Tm [(SH)-1(2-b)1(in)-1(d)1(in)-1(g)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 64.0759964 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 68.5759964 89.72200012 Tm [(mot)1(ifs)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 95.76499939 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 100.26499939 89.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 112.54299927 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 117.04299927 89.72200012 Tm [(v-C)1(rk)-1(.)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 142.18400574 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 146.68400574 89.72200012 Tm [(By)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 157.09500122 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 161.59500122 89.72200012 Tm [(immun)-1(o)1(prec)-1(ip)1(i)-1(t)1(at)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 252.35499573 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 256.85501099 89.72200012 Tm [(an)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(alysis,)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 25.02700043 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 29.52700043 105.3219986 Tm [(p13)-1(0)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 51.10900116 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 55.60900116 105.3219986 Tm [(Cas)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 70.76999664 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 75.26999664 105.3219986 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 89.95200348 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 94.45200348 105.3219986 Tm [(been)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 115.95899963 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 120.45899963 105.3219986 Tm [(sho)1(wn)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 148.53999329 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 153.03999329 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 162.11500549 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 166.61500549 105.3219986 Tm [(be)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 177.46899414 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 181.96899414 105.3219986 Tm [(hig)1(hly)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 208.36300659 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 212.86300659 105.3219986 Tm [(ph)1(osph)1(orylat)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ed)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 10.86299992 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 15.36299992 120.92199707 Tm [(at)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 23.69099998 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 28.19099998 120.92199707 Tm [(tyro)1(sin)-1(e)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 62.67900085 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 67.17900085 120.92199707 Tm [(residues)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 102.85800171 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 107.35800171 120.92199707 Tm [(subsequen)-1(t)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 157.39900208 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 161.89900208 120.92199707 Tm [(to)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 170.97399902 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 175.47399902 120.92199707 Tm [(either)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 200.41299438 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 204.91299438 120.92199707 Tm [(v-Src)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 226.67500305 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 231.17500305 120.92199707 Tm [(p60)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 247.47900391 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 251.97900391 120.92199707 Tm [(or)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 261.13699341 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 265.63699341 120.92199707 Tm [(v)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(-Cr)1(k)-1(-)1(me)-1(d)1(i)-1(a)1(ted)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 63.02600098 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 67.52600098 136.52200317 Tm [(tr)1(ansfor)1(m)-1(a)1(tion)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 131.70399475 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 136.20399475 136.52200317 Tm [(and)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 152.48100281 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 156.98100281 136.52200317 Tm [(to)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 166.05599976 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 170.55599976 136.52200317 Tm [(fo)1(rm)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 191.26699829 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 195.76699829 136.52200317 Tm [(st)1(able)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 221.50999451 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 226.00999451 136.52200317 Tm [(complexe)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(s)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 4.16599989 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 8.66600037 152.12199402 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 27.06200027 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 31.56200027 152.12199402 Tm [(bo)1(th)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 51.92599869 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 56.42599869 152.12199402 Tm [(of)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 65.26799774 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 69.76799774 152.12199402 Tm [(th)1(e)-1(se)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 93.04100037 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 97.54100037 152.12199402 Tm [(tr)1(ansfor)1(m)-1(ing)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 153.42599487 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 157.92599487 152.12199402 Tm [(pro)1(tein)-1(s)1(.)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 195.56500244 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 200.06500244 152.12199402 Tm [(p13)-1(0)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 221.64700317 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 226.14700317 152.12199402 Tm [(Cas)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 241.30799866 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 245.80799866 152.12199402 Tm [(beha)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(ves)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 13.99699974 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 18.49699974 167.72200012 Tm [(as)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 27.63800049 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 32.13800049 167.72200012 Tm [(an)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 42.6590004 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 47.1590004 167.72200012 Tm [(extremel)-1(y)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 89.42099762 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 93.92099762 167.72200012 Tm [(po)1(ten)-1(t)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 122.74900055 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 127.24900055 167.72200012 Tm [(subst)1(rat)1(e)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 167.09899902 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 171.59899902 167.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 183.8769989 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 188.3769989 167.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 219.68400574 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 224.18400574 167.72200012 Tm [(tyro)1(sin)-1(e)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 258.67199707 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 263.17199707 167.72200012 Tm [(ki)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 143.55000305 0.75 m 143.55000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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