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43.75799942 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -88 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -35.5 61.9640007 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -25 61.9640007 Tm [<00030004>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -1.375 61.9640007 Tm [(AU)1(P1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 24.80799866 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 77.30799866 61.9640007 Tm [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 82.55799866 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <</Lang (zh-CN) /MCID 13 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 14 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(A)1(UP)1(1)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 107.29199982 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 109.66600037 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 135.31599426 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 137.69000244 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 181.24899292 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 183.6230011 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 221.41900635 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F001000110012000D>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <</Lang (zh-CN) /MCID 28 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0014>] TJ ET EMC /P <</MCID 29 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 32 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 33 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 34 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 35 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0004>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001B000D>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(AU)1(P1)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 86.55799866 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 97.05799866 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 216.83399963 cm /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 250.3730011 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 283.9119873 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0022>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 317.45098877 cm /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700110025000D>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 350.98999023 m 416.75 350.98999023 l 416.75 382.19000244 l -1.45000005 382.19000244 l h f* Q q 1 0 0 1 0 350.98999023 cm /P <</MCID 73 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 410.1289978 cm q 1 g 0.375 0.75 m 154.7749939 0.75 l 154.7749939 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 155.7749939 -0.25 l 155.7749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 77 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 155.5249939 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 155.5249939 172.3500061 l h f* Q q 1 0 0 1 155.1499939 0 cm -0.625 -0.25 m 268.2749939 -0.25 l 268.2749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 79 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(This)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 128.977005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 133.477005 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 150.69900513 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 155.19900513 11.72200012 Tm [(contains)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 191.41400146 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 195.91400146 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 200.88900757 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 205.38900757 11.72200012 Tm [(do)1(main)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 238.21600342 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 242.71600342 11.72200012 Tm [(wit)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(h)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 5.54199982 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 10.04199982 27.3220005 Tm [(ho)1(mology)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 54.09700012 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 58.59700012 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 67.67199707 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 72.17199707 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 86.17299652 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 90.67299652 27.3220005 Tm [(anci)-1(ent)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 122.10700226 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 126.60700226 27.3220005 Tm [(conse)-1(rv)1(e)-1(d)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 170.68400574 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 175.18400574 27.3220005 Tm [(region)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 203.14599609 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 207.64599609 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 216.48800659 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 220.98800659 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 234.98899841 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 239.48899841 27.3220005 Tm [(arch)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ain)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 12.91600037 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 17.41600037 42.92200089 Tm [(1)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 22.69400024 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 27.19400024 42.92200089 Tm [(gene)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 48.70999908 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 53.20999908 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 69.48699951 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 73.98699951 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 78.96199799 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 83.46199799 42.92200089 Tm [(do)1(main)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 116.28900146 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 120.78900146 42.92200089 Tm [(th)1(at)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 138.01100159 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 142.51100159 42.92200089 Tm [(may)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 160.68200684 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 165.18200684 42.92200089 Tm [(be)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 176.03599548 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 180.53599548 42.92200089 Tm [(involved)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 216.90499878 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 221.40499878 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 229.34599304 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 233.84599304 42.92200089 Tm [(bindi)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ng)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 11.30300045 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 15.80300045 58.52199936 Tm [(ubiquitin-)1(c)-1(onjugat)1(ing)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 109.88999939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 114.38999939 58.52199936 Tm [(en)-1(z)1(y)-1(mes.)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 154.10299683 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 158.60299683 58.52199936 Tm [(The)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 174.41000366 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 178.91000366 58.52199936 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 210.21699524 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 214.71699524 58.52199936 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 252.22399902 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(by)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 10.51200008 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 15.01200008 74.12200165 Tm [(th)1(is)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 30.46800041 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 34.9679985 74.12200165 Tm [(gene)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 56.48400116 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 60.98400116 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 75.66600037 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 80.16600037 74.12200165 Tm [(been)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 101.67299652 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 106.17299652 74.12200165 Tm [(sho)1(wn)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 134.2539978 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 138.7539978 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 147.82899475 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 152.32899475 74.12200165 Tm [(bind)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 171.7749939 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 176.2749939 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 185.3500061 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 189.8500061 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 203.85099792 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 208.35099792 74.12200165 Tm [(conse)-1(rv)1(e)-1(d)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 252.42799377 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(membrane-pr)1(oximal)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 88.34300232 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 92.84300232 89.72200012 Tm [(seque)-1(nce)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 133.69000244 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 138.19000244 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 147.03199768 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 151.53199768 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 165.53300476 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 170.03300476 89.72200012 Tm [(cy)-1(t)1(oplas)1(mi)-1(c)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 221.00999451 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 225.50999451 89.72200012 Tm [(ta)1(il)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 238.62800598 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 243.12800598 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 251.97000122 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 256.47000122 89.72200012 Tm [(i)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ntegrin)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 31.13999939 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 35.63999939 105.3219986 Tm [(alph)1(a\(IIb\))] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 76.32499695 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 80.82499695 105.3219986 Tm [(subunits.)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 119.45700073 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 123.95700073 105.3219986 Tm [(These)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 149.03700256 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 153.53700256 105.3219986 Tm [(subunits)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 190.00300598 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 194.50300598 105.3219986 Tm [(play)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 212.38400269 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 216.88400269 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 221.85899353 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 226.35899353 105.3219986 Tm [(cru)-1(cial)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 254.13200378 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(role)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 16.65999985 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 21.15999985 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 29.10099983 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 33.60100174 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 47.60200119 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 52.10200119 120.92199707 Tm [(integrin)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 85.63700104 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 90.13700104 120.92199707 Tm [(alph)1(a\(IIb\)b)1(e)-1(t)1(a\(3\))] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 161.29299927 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 165.79299927 120.92199707 Tm [(inside-out)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 209.67199707 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 214.17199707 120.92199707 Tm [(signalling)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 255.4980011 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(in)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 7.94099998 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 12.44099998 136.52200317 Tm [(plat)1(el)-1(ets)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 49.03900146 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 53.53900146 136.52200317 Tm [(and)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 69.81600189 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 74.31600189 136.52200317 Tm [(megakaryocy)-1(t)1(e)-1(s)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 144.28599548 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 148.78599548 136.52200317 Tm [(th)1(at)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 166.00799561 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 170.50799561 136.52200317 Tm [(leads)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 192.90699768 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 197.40699768 136.52200317 Tm [(to)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 206.48199463 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 210.98199463 136.52200317 Tm [(plat)1(el)-1(et)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 243.41400146 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 247.91400146 136.52200317 Tm [(ag)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(gr)1(e)-1(ga)1(tion)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 42.04700089 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 46.54700089 152.12199402 Tm [(and)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 62.82400131 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 67.3239975 152.12199402 Tm [(th)1(rombus)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 109.26999664 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 113.76999664 152.12199402 Tm [(fo)1(rmatio)1(n)-1(.)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 158.63800049 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 163.13800049 152.12199402 Tm [(This)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 180.3999939 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 184.8999939 152.12199402 Tm [(gene)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 206.41600037 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 210.91600037 152.12199402 Tm [(overlap)1(s)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 247.18800354 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 251.68800354 152.12199402 Tm [(t)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(he)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 10.64799976 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 15.14799976 167.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 36.66400146 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 41.16400146 167.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 53.44200134 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 57.94200134 167.72200012 Tm [(mito)1(c)-1(ho)1(n)-1(d)1(rial)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 118.125 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 122.625 167.72200012 Tm [(serine)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 148.3809967 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 152.8809967 167.72200012 Tm [(pro)1(tease)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 190.4940033 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 194.9940033 167.72200012 Tm [(25)-1(.)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 207.71600342 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 172.3500061 cm q 1 g 0.375 0.75 m 154.7749939 0.75 l 154.7749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 155.7749939 -0.25 l 155.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 265 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 266 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 155.5249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 155.5249939 16.35000038 l h f* Q q 1 0 0 1 155.1499939 0 cm -0.625 -0.25 m 268.2749939 -0.25 l 268.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 267 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(WB,)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 47.37799835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 51.87799835 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 67.50499725 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 188.69999695 cm q 1 g 0.375 0.75 m 154.7749939 0.75 l 154.7749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 155.7749939 -0.25 l 155.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 273 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 278 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 155.5249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 155.5249939 16.35000038 l h f* Q q 1 0 0 1 155.1499939 0 cm -0.625 -0.25 m 268.2749939 -0.25 l 268.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 279 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(AU)1(P1)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 23.83600044 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 205.05001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 155.1499939 0.75 m 155.1499939 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 155.1499939 173.1000061 m 155.1499939 188.70001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 155.1499939 189.45001221 m 155.1499939 205.05001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 205.05001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 172.7250061 m 422.42498779 172.7250061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 189.07501221 m 422.42498779 189.07501221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 205.42501831 m 423.17498779 205.42501831 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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