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  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 26 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000B>] TJ ET EMC /P <</MCID 27 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(FRP1;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 87.08100128 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 89.45500183 12.82499981 Tm [(MEC1;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 117.28900146 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 119.66300201 12.82499981 Tm [(SC)-1(K)1(L)-1(;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 142.76499939 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 145.13900757 12.82499981 Tm [(FC)-1(TCS)-1(;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 173.91099548 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 176.28500366 12.82499981 Tm [(SC)-1(K)1(L)-1(1)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 201.89900208 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0010>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001100120013>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00140015>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<0016>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [(ATR)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 58.89300156 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 61.26699829 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<0018>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 69.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 84 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 68 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0019001A001B000E>] TJ ET EMC /P <</MCID 69 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001C0004>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001D001E001F0020>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0021>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 82 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0022>] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 91 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00060007001B0024>] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 98 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 99 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 100 >> BDC BT /FAAACI 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 101 >> BDC BT /FAAADC 18 Tf 1 0 0 -1 42 20.17499924 Tm 1 Tr 0.51428574 w /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 102 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 12.89099979 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 159.2749939 0.75 l 159.2749939 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 160.2749939 -0.25 l 160.2749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 103 >> BDC BT /FAAADF 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 104 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 160.0249939 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 160.0249939 172.3500061 l h f* Q q 1 0 0 1 159.6499939 0 cm -0.625 -0.25 m 263.7749939 -0.25 l 263.7749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 105 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(belongs)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 193.54499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 198.04499817 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 212.04600525 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 216.54600525 11.72200012 Tm [(PI3/PI4)-1(-)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 27.08799934 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 31.58799934 27.3220005 Tm [(fa)1(mi)-1(ly,)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 59.83599854 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 64.33599854 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 80.61299896 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 85.11299896 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 91.6740036 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 96.1740036 27.3220005 Tm [(most)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 117.84799957 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 122.34799957 27.3220005 Tm [(cl)-1(o)1(se)-1(ly)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 151.40899658 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 155.90899658 27.3220005 Tm [(related)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 186.03799438 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 190.53799438 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 199.61300659 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 204.11300659 27.3220005 Tm [(ATM,)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 226.56500244 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 231.06500244 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 236.03999329 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 240.53999329 27.3220005 Tm [(pro)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(tein)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 16.39999962 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 20.89999962 42.92200089 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 47.98799896 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 52.48799896 42.92200089 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 89.99500275 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 94.49500275 42.92200089 Tm [(by)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 105.00700378 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 109.50700378 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 123.50800323 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 128.00799561 42.92200089 Tm [(gene)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 149.52400208 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 154.02400208 42.92200089 Tm [(mutat)1(ed)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 190.54699707 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 195.04699707 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 202.98800659 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 207.48800659 42.92200089 Tm [(at)1(axia)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 232.72099304 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 237.22099304 42.92200089 Tm [(tela)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ngiec)-1(t)1(asia.)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 45.34700012 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 49.84700012 58.52199936 Tm [(This)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 67.10900116 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 71.60900116 58.52199936 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 102.91600037 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 107.41600037 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 123.69300079 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 128.19299316 58.52199936 Tm [(ATM)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 148.47799683 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 152.97799683 58.52199936 Tm [(sha)1(re)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 176.20300293 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 180.70300293 58.52199936 Tm [(similarit)1(y)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 219.41000366 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 223.91000366 58.52199936 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 242.30599976 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 246.80599976 58.52199936 Tm [(S)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(chizosa)1(c)-1(charo)1(my)-1(ces)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 87.41999817 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 91.91999817 74.12200165 Tm [(po)1(mbe)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 122.67700195 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 127.17700195 74.12200165 Tm [(rad)1(3)-1(,)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 148.78900146 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 153.28900146 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 158.26400757 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 162.76400757 74.12200165 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 177.17399597 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 181.67399597 74.12200165 Tm [(cy)-1(cle)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 202.96600342 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 207.46600342 74.12200165 Tm [(che)-1(ckpoint)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 254.80400085 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 21.51600075 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 26.01600075 89.72200012 Tm [(required)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 62.55699921 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 67.05699921 89.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 79.33499908 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 83.83499908 89.72200012 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 98.24500275 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 102.74500275 89.72200012 Tm [(cy)-1(cle)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 124.03700256 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 128.53700256 89.72200012 Tm [(arr)1(e)-1(st)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 153.00999451 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 157.50999451 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 173.78700256 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 178.28700256 89.72200012 Tm [(DNA)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 198.79200745 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 203.29200745 89.72200012 Tm [(da)1(mage)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 238.29400635 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 242.79400635 89.72200012 Tm [(re)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(pa)1(i)-1(r)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 16.55400085 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 21.05400085 105.3219986 Tm [(in)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 28.99500084 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 33.49499893 105.3219986 Tm [(response)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 72.49199677 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 76.99199677 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 86.06700134 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 90.56700134 105.3219986 Tm [(DNA)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 111.0719986 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 115.5719986 105.3219986 Tm [(da)1(mage.)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 152.74099731 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 157.24099731 105.3219986 Tm [(This)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 174.50300598 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 179.00300598 105.3219986 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 206.09100342 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 210.59100342 105.3219986 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 225.272995 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 229.772995 105.3219986 Tm [(been)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 251.27999878 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(sho)1(wn)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 28.08099937 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 32.58100128 120.92199707 Tm [(to)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 41.65599823 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 46.15599823 120.92199707 Tm [(ph)1(osph)1(orylate)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 108.37400055 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 112.87400055 120.92199707 Tm [(che)-1(ckpoint)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 160.21200562 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 164.71200562 120.92199707 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 191.80000305 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 196.30000305 120.92199707 Tm [(CHK1)-1(,)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 222.43899536 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 226.93899536 120.92199707 Tm [(che)-1(ck)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 22.76399994 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 27.26399994 136.52200317 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 62.73699951 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 67.23699951 136.52200317 Tm [(RA)1(D1)-1(7,)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 99.02300262 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 103.52300262 136.52200317 Tm [(and)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 119.80000305 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 124.30000305 136.52200317 Tm [(RA)1(D9)-1(,)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 150.80799866 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 155.30799866 136.52200317 Tm [(as)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 164.44900513 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 168.94900513 136.52200317 Tm [(well)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 185.95100403 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 190.45100403 136.52200317 Tm [(as)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 199.59199524 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 204.09199524 136.52200317 Tm [(tumor)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 230.58200073 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 235.08200073 136.52200317 Tm [(sup)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(presso)1(r)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 31.78100014 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 36.28099823 152.12199402 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 67.58799744 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 72.08799744 152.12199402 Tm [(BRCA1.)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 103.40799713 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 107.90799713 152.12199402 Tm [(Mutat)1(ions)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 151.75700378 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 156.25700378 152.12199402 Tm [(of)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 165.09899902 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 169.59899902 152.12199402 Tm [(th)1(is)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 185.05499268 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 189.55499268 152.12199402 Tm [(gene)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 211.07099915 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 215.57099915 152.12199402 Tm [(are)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 229.08900452 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 233.58900452 152.12199402 Tm [(asso)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(ci)-1(a)1(ted)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 26.09900093 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 30.59900093 167.72200012 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 48.99499893 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 53.49499893 167.72200012 Tm [(Se)-1(cke)-1(l)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 80.70999908 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 85.20999908 167.72200012 Tm [(syndrome.)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 130.30700684 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 134.80700684 167.72200012 Tm [(An)] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 146.68499756 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 151.18499756 167.72200012 Tm [(alt)1(e)-1(rnat)1(ive)-1(ly)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 203.70799255 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 208.20799255 167.72200012 Tm [(splice)-1(d)] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 238.28900146 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 242.78900146 167.72200012 Tm [(tr)1(a)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 159.6499939 0.75 m 159.6499939 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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6 0 obj
<</Length1 127 0 R/Length 27692>>stream
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