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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.20001221 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 88 0 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 49.67599869 23.67700005 Tm 0 Tr [(CSK)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 89.25 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 199.69000244 23.67700005 Tm 0 Tr [( )] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 210.69000244 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 -88 43.75799942 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -88 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <> BDC BT 1 0 0 -1 -35.5 61.9640007 Tm [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -11.875 61.9640007 Tm [(CS)-1(K)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 6.62799835 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 59.12800598 61.9640007 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.37800598 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CSK)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.98600006 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.63600159 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.00999451 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.56900024 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.94299316 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.73899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F001000110012000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CS)-1(K)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.87799835 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 216.83399963 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001F000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 250.3730011 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0020002100220023000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.36599731 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.72799683 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.102005 12.82499981 Tm [(Rat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.3500061 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 283.9119873 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002400250026000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 317.45098877 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700110027000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 350.98999023 m 416.75 350.98999023 l 416.75 382.19000244 l -1.45000005 382.19000244 l h f* Q q 1 0 0 1 0 350.98999023 cm /P <> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 382.19000244 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 410.1289978 cm q 1 g 0.375 0.75 m 157.0249939 0.75 l 157.0249939 203.55000305 l 0.375 203.55000305 l h f* Q q -0.625 -0.25 m 158.0249939 -0.25 l 158.0249939 204.55000305 l -0.625 204.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 105.3219986 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.29199982 105.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 157.7749939 0.75 m 422.42498779 0.75 l 422.42498779 203.55000305 l 157.7749939 203.55000305 l h f* Q q 1 0 0 1 157.3999939 0 cm -0.625 -0.25 m 266.0249939 -0.25 l 266.0249939 204.55000305 l -0.625 204.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Non-r)1(e)-1(ce)-1(p)1(tor)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.90000153 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.40000153 11.72200012 Tm [(tyro)1(sin)-1(e-p)1(rot)1(e)-1(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.08799744 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.58799744 11.72200012 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.67599487 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.17599487 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.397995 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.897995 11.72200012 Tm [(plays)] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.94500732 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.44500732 11.72200012 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.96600342 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.46600342 11.72200012 Tm [(impo)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(rt)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.66300011 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.16300011 27.3220005 Tm [(role)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.82300186 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.32300186 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.26399994 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.76399994 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.76499939 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.26499939 27.3220005 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.4960022 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.9960022 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.83799744 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.33799744 27.3220005 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.7480011 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.2480011 27.3220005 Tm [(gr)1(owt)1(h,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.33000183 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.83000183 27.3220005 Tm [(dif)1(fe)-1(r)1(e)-1(nt)1(i)-1(a)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 2.16700006 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 6.66699982 42.92200089 Tm [(migra)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.67900085 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.17900085 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.45600128 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.95600128 42.92200089 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.41500092 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.91500092 42.92200089 Tm [(response.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.07899475 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.57899475 42.92200089 Tm [(Pho)1(spho)1(ryl)-1(a)1(tes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.72099304 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.22099304 42.92200089 Tm [(tyro)1(si)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.65200043 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.15200043 58.52199936 Tm [(residues)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.83100128 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.33100128 58.52199936 Tm [(located)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.15200043 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.65200043 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.59300232 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.09300232 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.09400177 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.59400177 58.52199936 Tm [(C-t)1(e)-1(r)1(min)-1(a)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.147995 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.647995 58.52199936 Tm [(ta)1(il)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.93200684 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.43200684 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.27400208 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.77400208 58.52199936 Tm [(Src-fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.89300537 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ki)-1(na)1(se)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.25399971 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.75400162 74.12200165 Tm [(\(SFKs\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.61999893 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.12000275 74.12200165 Tm [(inc)-1(luding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.97000122 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.47000122 74.12200165 Tm [(LCK,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.98899841 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.48899841 74.12200165 Tm [(SRC,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.7460022 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.2460022 74.12200165 Tm [(HCK,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.10699463 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.60699463 74.12200165 Tm [(FYN,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.30299377 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.80299377 74.12200165 Tm [(LYN)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.16999817 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.66999817 74.12200165 Tm [(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.82800293 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.32800293 74.12200165 Tm [(YE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(S1)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.63899994 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.13899994 89.72200012 Tm [(Up)1(on)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.87400055 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.37400055 89.72200012 Tm [(ta)1(il)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.49200058 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.99200058 89.72200012 Tm [(ph)1(osph)1(orylation,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.93200684 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.43200684 89.72200012 Tm [(Src-fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.55099487 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.05099487 89.72200012 Tm [(members)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.48100281 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.98100281 89.72200012 Tm [(en)-1(g)1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ge)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.86299992 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.36299992 105.3219986 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.30400085 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.80400085 105.3219986 Tm [(intra)1(mole)-1(cular)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.03099823 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.53099823 105.3219986 Tm [(interactions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.03700256 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.53700256 105.3219986 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.60899353 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.10899353 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.11000061 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.61000061 105.3219986 Tm [(ph)1(osph)1(oty)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ros)1(i)-1(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.37199974 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.87199974 120.92199707 Tm [(ta)1(il)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.99000168 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.49000168 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.76699829 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.26699829 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.26799774 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.76799774 120.92199707 Tm [(SH)-1(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.2009964 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.7009964 120.92199707 Tm [(do)1(main)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.52799988 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.02799988 120.92199707 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.25 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.75 120.92199707 Tm [(result)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.75300598 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.25300598 120.92199707 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.19400024 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.69400024 120.92199707 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.21499634 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.71499634 120.92199707 Tm [(inac)-1(t)1(ive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.72198486 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(conforma)1(tion.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.64899826 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.14900208 136.52200317 Tm [(To)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.02999878 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.52999878 136.52200317 Tm [(inhibit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.90399933 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.40399933 136.52200317 Tm [(SFKs,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.42500305 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.92500305 136.52200317 Tm [(CSK)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.85299683 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.35299683 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.91400146 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.41400146 136.52200317 Tm [(rec)-1(ruit)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.06399536 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.56399536 136.52200317 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.63900757 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.13900757 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.13999939 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.63999939 136.52200317 Tm [(pl)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(asma)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.54800034 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.04800034 152.12199402 Tm [(membrane)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.83200073 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.33200073 152.12199402 Tm [(via)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.4260025 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.9260025 152.12199402 Tm [(binding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.07000732 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.57000732 152.12199402 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.64500427 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.14500427 152.12199402 Tm [(tr)1(ansme)-1(mb)1(rane)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.40499878 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.90499878 152.12199402 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.37800598 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.15799999 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.65799999 167.72200012 Tm [(ad)1(apt)1(e)-1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.00799942 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.50799942 167.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.98100281 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.48100281 167.72200012 Tm [(located)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.30200195 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.80200195 167.72200012 Tm [(ne)-1(a)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.86500549 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.36500549 167.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.36599731 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.86599731 167.72200012 Tm [(plas)1(ma)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.55700684 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.05700684 167.72200012 Tm [(membrane.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.00799561 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 183.32200623 Tm [(Suppresses)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.38399887 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.88399887 183.32200623 Tm [(signaling)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.81500244 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.31500244 183.32200623 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.82700348 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.32700348 183.32200623 Tm [(var)1(i)-1(o)1(u)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.29100037 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.79100037 183.32200623 Tm [(surfa)1(c)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.65400696 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.15400696 183.32200623 Tm [(rec)-1(ept)1(ors,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.90800476 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.40800476 183.32200623 Tm [(inc)-1(lud)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 198.92199707 Tm [(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.69799995 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.19799995 198.92199707 Tm [(T-ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.65999985 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.15999985 198.92199707 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.58200073 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.08200073 198.92199707 Tm [(\(TCR\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.14900208 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.64900208 198.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.92599487 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.42599487 198.92199707 Tm [(B-c)-1(ell)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.37600708 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.87600708 198.92199707 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.29800415 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.79800415 198.92199707 Tm [(\(BCR\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.35299683 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.85299683 198.92199707 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.36500549 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.86500549 198.92199707 Tm [(p)] TJ ET EMC Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 203.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.3999939 0.75 m 157.3999939 203.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 203.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 203.92500305 m 423.17498779 203.92500305 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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