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[<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(CS)-1(F1R)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 105.02100372 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 157.52099609 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 168.02099609 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CSF)-1(1R)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 110.0039978 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 112.37799835 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 138.02799988 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 140.4019928 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 183.96099854 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 186.33500671 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 224.1309967 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(FMS)-1(,)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 84.2460022 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 86.62000275 12.82499981 Tm [(CS)-1(FR,)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 110.18900299 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 112.56300354 12.82499981 Tm [(FIM2,)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 136.95199585 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 139.32600403 12.82499981 Tm [(HDL)-1(S,)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 164.18699646 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 166.56100464 12.82499981 Tm [(C-F)-1(MS,)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 196.61999512 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 198.9940033 12.82499981 Tm [(CD115,)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 229.63800049 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 232.01199341 12.82499981 Tm [(CS)-1(F-1R,)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 264.11700439 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 266.49099731 12.82499981 Tm [(M-CS)-1(F-R)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 302.8460083 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001C000D>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CS)-1(F1R)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 89.27100372 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 66 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 67 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)1(,)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 130.96800232 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 133.34199524 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002200230024000D>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 85 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 86 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 88 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 154.7749939 0.75 l 154.7749939 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 155.7749939 -0.25 l 155.7749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 89 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 90 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 155.5249939 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 155.5249939 172.3500061 l h f* Q q 1 0 0 1 155.1499939 0 cm -0.625 -0.25 m 268.2749939 -0.25 l 268.2749939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 91 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 184.16700745 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 188.66700745 11.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 225.08900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 229.58900452 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 241.86700439 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 246.36700439 11.72200012 Tm [(col)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ony)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 16.03100014 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 20.53100014 27.3220005 Tm [(st)1(i)-1(mulat)1(in)-1(g)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 68.84400177 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 73.34400177 27.3220005 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 98.46299744 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 102.96299744 27.3220005 Tm [(1,)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 110.40699768 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 114.90699768 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 119.88200378 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 124.38200378 27.3220005 Tm [(cy)-1(t)1(oki)-1(ne)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 160.68099976 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 165.18099976 27.3220005 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 190.27799988 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 194.77799988 27.3220005 Tm [(controls)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 229.6309967 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 234.1309967 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 248.13200378 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 252.63200378 27.3220005 Tm [(p)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(rod)1(uc)-1(t)1(i)-1(o)1(n)-1(,)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 44.15599823 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 48.65599823 42.92200089 Tm [(dif)1(fe)-1(r)1(e)-1(nt)1(i)-1(a)1(tion,)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 112.14800262 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 116.64800262 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 132.92500305 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 137.42500305 42.92200089 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 173.16600037 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 177.66600037 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 186.50799561 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 191.00799561 42.92200089 Tm [(macrop)1(hages.)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 251.54699707 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(This)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 17.26199913 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 21.76199913 58.52199936 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 58.18399811 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 62.68399811 58.52199936 Tm [(mediat)1(e)-1(s)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 101.97599792 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 106.47599792 58.52199936 Tm [(most)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 128.1499939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 132.6499939 58.52199936 Tm [(if)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 138.16499329 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 142.66499329 58.52199936 Tm [(not)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 157.28599548 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 161.78599548 58.52199936 Tm [(all)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 171.55099487 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 176.05099487 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 184.89300537 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 189.39300537 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 203.39399719 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 207.89399719 58.52199936 Tm [(biolo)1(gic)-1(a)1(l)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 249.91000366 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 254.41000366 58.52199936 Tm [(e)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ff)1(e)-1(cts)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 23.37899971 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 27.87899971 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 36.72100067 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 41.22100067 74.12200165 Tm [(th)1(is)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 56.67699814 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 61.17699814 74.12200165 Tm [(cy)-1(t)1(oki)-1(ne.)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 99.64199829 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 104.14199829 74.12200165 Tm [(Ligand)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 133.19000244 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 137.69000244 74.12200165 Tm [(binding)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 170.83399963 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 175.33399963 74.12200165 Tm [(activat)1(es)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 212.89399719 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 217.39399719 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 231.39500427 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 235.89500427 74.12200165 Tm [(rec)-1(ep)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(to)1(r)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 12.51099968 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 17.01099968 89.72200012 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 44.09899902 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 48.59899902 89.72200012 Tm [(th)1(rough)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 83.4960022 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 87.9960022 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 92.97100067 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 97.47100067 89.72200012 Tm [(pro)1(c)-1(ess)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 130.32899475 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 134.82899475 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 143.67100525 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 148.17100525 89.72200012 Tm [(oligo)1(me)-1(riz)1(ation)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 215.94799805 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 220.44799805 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 236.7250061 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 241.2250061 89.72200012 Tm [(tr)1(an)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(sph)1(osph)1(orylatio)1(n)-1(.)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 77.10600281 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 81.60600281 105.3219986 Tm [(The)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 97.41300201 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 101.91300201 105.3219986 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 139.41999817 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 143.91999817 105.3219986 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 175.227005 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 179.727005 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 186.28799438 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 190.78799438 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 195.76300049 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 200.26300049 105.3219986 Tm [(tyro)1(sin)-1(e)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 234.75100708 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 239.25100708 105.3219986 Tm [(ki)-1(na)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(se)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 9.27200031 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 13.77200031 120.92199707 Tm [(tr)1(ansme)-1(mb)1(rane)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 82.03199768 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 86.53199768 120.92199707 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 122.95400238 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 127.45400238 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 143.73100281 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 148.23100281 120.92199707 Tm [(member)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 184.49499512 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 188.99499512 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 197.83700562 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 202.33700562 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 216.33799744 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 220.83799744 120.92199707 Tm [(CSF1)-1(/PD)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(GF)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 11.47399998 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 15.97399998 136.52200317 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 52.39599991 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 56.89599991 136.52200317 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 82.97799683 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 87.47799683 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 96.31999969 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 100.81999969 136.52200317 Tm [(tyro)1(sin)-1(e-p)1(rot)1(e)-1(in)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 170.50799561 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 175.00799561 136.52200317 Tm [(ki)-1(na)1(se)-1(s.)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 208.42799377 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 212.92799377 136.52200317 Tm [(Mutat)1(ions)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 256.77700806 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(in)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 7.94099998 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 12.44099998 152.12199402 Tm [(th)1(is)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 27.89699936 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 32.39699936 152.12199402 Tm [(gene)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 53.9129982 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 58.4129982 152.12199402 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 78.76000214 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 83.26000214 152.12199402 Tm [(been)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 104.76699829 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 109.26699829 152.12199402 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 154.39399719 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 158.89399719 152.12199402 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 177.28999329 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 181.78999329 152.12199402 Tm [(a)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 186.76499939 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 191.26499939 152.12199402 Tm [(predisp)1(ositio)1(n)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 252.91999817 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(to)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 9.07499981 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 13.57499981 167.72200012 Tm [(mye)-1(loid)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 48.14699936 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 52.64699936 167.72200012 Tm [(malignancy)-1(.)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 104.11100006 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 108.61100006 167.72200012 Tm [(The)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 124.41799927 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 128.91799927 167.72200012 Tm [(first)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 145.38900757 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 149.88900757 167.72200012 Tm [(intro)1(n)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 175.88699341 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 180.38699341 167.72200012 Tm [(of)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 189.22900391 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 193.72900391 167.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 209.18499756 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 213.68499756 167.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 235.20100403 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 239.70100403 167.72200012 Tm [(cont)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 155.1499939 0.75 m 155.1499939 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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