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q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(CS)-1(F1R\(Pho)-1(spho)-1(-Tyr)1(809\))] TJ ET EMC /P <</MCID 8 >> BDC BT 1 0 0 -1 178.62800598 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 183.87800598 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 236.37800598 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 246.87800598 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CSF)-1(1R\(P)1(h)-1(osp)-1(ho-)-1(Ty)1(r809\))] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 186.23699951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 188.61099243 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 214.26100159 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 216.63499451 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 260.19400024 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 262.56799316 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 300.36401367 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(FMS)-1(;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 84.43599701 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 86.80999756 12.82499981 Tm [(CS)-1(FR;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 110.56800079 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 112.94200134 12.82499981 Tm [(FIM2;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 137.52099609 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 139.89500427 12.82499981 Tm [(HDL)-1(S;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 164.94500732 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 167.31900024 12.82499981 Tm [(C-F)-1(MS;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 197.56799316 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 199.94200134 12.82499981 Tm [(CD115;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 230.7749939 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 233.14900208 12.82499981 Tm [(CS)-1(F-1R;)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 265.44400024 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 267.81799316 12.82499981 Tm [(M-CS)-1(F-R)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 304.17300415 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0011000D>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001200130014>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00150016>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<00170018>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0019000D>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CS)-1(F1R\(Pho)-1(spho)-1(-Tyr)1(809\))] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 165.50300598 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001B000D>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F000D>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002000210022000F000D>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00230004>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002400250026000D>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700220027000D>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 85 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 86 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 88 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 138.2749939 0.75 l 138.2749939 94.34999847 l 0.375 94.34999847 l h f* Q q -0.625 -0.25 m 139.2749939 -0.25 l 139.2749939 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 89 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 50.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 90 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.29199982 50.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 139.0249939 0.75 m 422.42498779 0.75 l 422.42498779 94.34999847 l 139.0249939 94.34999847 l h f* Q q 1 0 0 1 138.6499939 0 cm -0.625 -0.25 m 284.7749939 -0.25 l 284.7749939 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 91 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 184.16700745 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 188.66700745 11.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 225.08900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 229.58900452 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 241.86700439 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 246.36700439 11.72200012 Tm [(colony)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 275.02801514 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(st)1(i)-1(mulat)1(in)-1(g)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 48.31299973 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 52.81299973 27.3220005 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 77.93199921 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 82.43199921 27.3220005 Tm [(1,)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 89.87599945 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 94.37599945 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 99.35099792 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 103.85099792 27.3220005 Tm [(cy)-1(t)1(oki)-1(ne)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 140.1499939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 144.6499939 27.3220005 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 169.74699402 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 174.24699402 27.3220005 Tm [(controls)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 209.1000061 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 213.6000061 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 227.60099792 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 232.10099792 27.3220005 Tm [(pro)1(duc)-1(t)1(io)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(n,)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 7.71199989 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 12.21199989 42.92200089 Tm [(dif)1(fe)-1(r)1(e)-1(nt)1(i)-1(a)1(tion,)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 75.70400238 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 80.20400238 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 96.48100281 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 100.98100281 42.92200089 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 136.72200012 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 141.22200012 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 150.06399536 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 154.56399536 42.92200089 Tm [(macrop)1(hages.)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 215.10299683 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 219.60299683 42.92200089 Tm [(This)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 236.86500549 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 241.36500549 42.92200089 Tm [(rec)-1(ept)1(o)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(r)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 3.43700004 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 7.9369998 58.52199936 Tm [(mediat)1(e)-1(s)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 47.22900009 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 51.72900009 58.52199936 Tm [(most)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 73.40299988 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 77.90299988 58.52199936 Tm [(if)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 83.41799927 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 87.91799927 58.52199936 Tm [(not)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 102.53900146 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 107.03900146 58.52199936 Tm [(all)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 116.80400085 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 121.30400085 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 130.14599609 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 134.64599609 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 148.64700317 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 153.14700317 58.52199936 Tm [(biolo)1(gic)-1(a)1(l)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 195.16299438 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 199.66299438 58.52199936 Tm [(effec)-1(t)1(s)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 228.147995 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 232.647995 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 241.49000549 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 245.99000549 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 261.4460144 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 265.9460144 58.52199936 Tm [(cy)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(to)1(k)-1(ine.)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 29.18799973 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 33.68799973 74.12200165 Tm [(Ligand)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 62.73600006 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 67.23600006 74.12200165 Tm [(binding)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 100.37999725 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 104.87999725 74.12200165 Tm [(activat)1(es)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 142.44000244 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 146.94000244 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 160.94099426 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 165.44099426 74.12200165 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 201.86300659 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 206.36300659 74.12200165 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 233.45100403 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 237.95100403 74.12200165 Tm [(th)1(rough)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 272.84799194 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 4.9749999 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 9.47500038 89.72200012 Tm [(pro)1(c)-1(ess)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 42.33300018 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 46.83300018 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 55.67499924 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 60.17499924 89.72200012 Tm [(oligo)1(me)-1(riz)1(ation)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 127.95200348 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 132.45199585 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 148.72900391 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 153.22900391 89.72200012 Tm [(tr)1(anspho)1(spho)1(ry)-1(la)1(tion.)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 247.64599609 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 94.34999847 cm q /GS2 gs 1 g 0.375 0.75 m 138.2749939 0.75 l 138.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 139.2749939 -0.25 l 139.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 198 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 199 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 139.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 139.0249939 16.35000038 l h f* Q q 1 0 0 1 138.6499939 0 cm -0.625 -0.25 m 284.7749939 -0.25 l 284.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 200 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 110.69999695 cm q /GS2 gs 1 g 0.375 0.75 m 138.2749939 0.75 l 138.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 139.2749939 -0.25 l 139.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 202 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 207 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 139.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 139.0249939 16.35000038 l h f* Q q 1 0 0 1 138.6499939 0 cm -0.625 -0.25 m 284.7749939 -0.25 l 284.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 208 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CSF1)-1(R\(P)1(hosp)1(ho-Tyr80)-1(9\))] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 104.19400024 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 127.05000305 cm q /GS2 gs 1 g 0.375 0.75 m 138.2749939 0.75 l 138.2749939 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 139.2749939 -0.25 l 139.2749939 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 210 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 211 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.89400101 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 139.0249939 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 139.0249939 31.95000076 l h f* Q q 1 0 0 1 138.6499939 0 cm -0.625 -0.25 m 284.7749939 -0.25 l 284.7749939 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 212 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Pept)1(i)-1(d)1(e)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 32.97200012 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 37.47200012 11.72200012 Tm [(seque)-1(nce)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 78.31900024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 82.81900024 11.72200012 Tm [(aro)1(u)-1(nd)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 113.80000305 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 118.30000305 11.72200012 Tm [(ph)1(osph)1(orylation)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 189.07400513 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 193.57400513 11.72200012 Tm [(site)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 208.59500122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 213.09500122 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 221.93699646 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 226.43699646 11.72200012 Tm [(tyro)1(sin)-1(e)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 260.92498779 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 265.42498779 11.72200012 Tm [(80)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(9)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 5.27799988 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 9.77799988 27.3220005 Tm [(\(S-N-)1(Y\(p\)-)1(I-V\))] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 69.7990036 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 74.2990036 27.3220005 Tm [(derived)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 106.58100128 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 111.08100128 27.3220005 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 131.79200745 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 136.29200745 27.3220005 Tm [(Hu)-1(ma)1(n)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 167.7519989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 172.2519989 27.3220005 Tm [(M-CSF)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 200.93499756 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 205.43499756 27.3220005 Tm [(Rec)-1(ept)1(or.)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 246.46200562 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 159 cm q /GS2 gs 1 g 0.375 0.75 m 138.2749939 0.75 l 138.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 139.2749939 -0.25 l 139.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 241 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 244 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 139.0249939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 139.0249939 16.35000038 l h f* Q q 1 0 0 1 138.6499939 0 cm -0.625 -0.25 m 284.7749939 -0.25 l 284.7749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 245 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(colony)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 28.6609993 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 33.1609993 11.72200012 Tm [(st)1(i)-1(mulat)1(in)-1(g)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 81.47399902 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 85.97399902 11.72200012 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 111.09300232 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 115.59300232 11.72200012 Tm [(1)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 120.8710022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 125.3710022 11.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 161.79299927 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 175.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 138.6499939 0.75 m 138.6499939 94.34999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 138.6499939 95.09999847 m 138.6499939 110.69999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 138.6499939 111.44999695 m 138.6499939 127.04999542 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 138.6499939 127.79999542 m 138.6499939 159 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 138.6499939 159.75 m 138.6499939 175.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 175.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 94.72499847 m 422.42498779 94.72499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 111.07499695 m 422.42498779 111.07499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 127.42499542 m 422.42498779 127.42499542 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 159.375 m 422.42498779 159.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 175.7250061 m 423.17498779 175.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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