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<</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(CS)-1(F1R\(Ab-809\))] TJ ET EMC /P <</MCID 8 >> BDC BT 1 0 0 -1 139.53500366 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 144.78500366 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 197.28500366 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 202.53500366 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(CSF)-1(1R\(A)1(b)-1(-809)1(\))] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 147.14399719 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 149.51800537 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 175.16799927 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 177.54200745 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 221.10099792 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 223.4750061 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 261.27099609 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(FMS)-1(;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 84.43599701 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 86.80999756 12.82499981 Tm [(CS)-1(FR;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 110.56800079 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 112.94200134 12.82499981 Tm [(FIM2;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 137.52099609 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 139.89500427 12.82499981 Tm [(HDL)-1(S;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 164.94500732 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 167.31900024 12.82499981 Tm [(C-F)-1(MS;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 197.56799316 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 199.94200134 12.82499981 Tm [(CD115;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 230.7749939 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 233.14900208 12.82499981 Tm [(CS)-1(F-1R;)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 265.44400024 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 267.81799316 12.82499981 Tm [(M-CS)-1(F-R)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 304.17300415 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001D>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001E000D>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 66 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001F000D>] TJ ET EMC /P <</MCID 67 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CS)-1(F1R\(Ab-809\))] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 126.41000366 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 70 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0020002100220023000D>] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002400250026000D>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120027000D>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 85 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 86 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q /GS2 gs 1 g 0.375 0.75 m 157.0249939 0.75 l 157.0249939 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 158.0249939 -0.25 l 158.0249939 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 88 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.7749939 0.75 m 422.375 0.75 l 422.375 141.1499939 l 157.7749939 141.1499939 l h f* Q q 1 0 0 1 157.3999939 0 cm -0.625 -0.25 m 265.9750061 -0.25 l 265.9750061 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 184.16700745 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 188.66700745 11.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 225.08900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 229.58900452 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 241.86700439 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 246.36700439 11.72200012 Tm [(co)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(lony)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 18.4260006 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 22.9260006 27.3220005 Tm [(st)1(i)-1(mulat)1(in)-1(g)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 71.23899841 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 75.73899841 27.3220005 Tm [(fa)1(c)-1(t)1(or)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 100.85800171 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 105.35800171 27.3220005 Tm [(1,)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 112.80200195 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 117.30200195 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 122.27700043 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 126.77700043 27.3220005 Tm [(cy)-1(t)1(oki)-1(ne)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 163.07600403 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 167.57600403 27.3220005 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 192.67300415 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 197.17300415 27.3220005 Tm [(controls)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 232.02600098 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 236.52600098 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 250.5269928 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(pro)1(duc)-1(t)1(ion,)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 49.90399933 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 54.40399933 42.92200089 Tm [(dif)1(fe)-1(r)1(e)-1(nt)1(i)-1(a)1(tion,)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 117.89600372 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 122.39600372 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 138.67300415 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 143.17300415 42.92200089 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 178.91400146 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 183.41400146 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 192.2559967 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 196.7559967 42.92200089 Tm [(macrop)1(hages.)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 257.29501343 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(This)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 17.26199913 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 21.76199913 58.52199936 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 58.18399811 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 62.68399811 58.52199936 Tm [(mediat)1(e)-1(s)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 101.97599792 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 106.47599792 58.52199936 Tm [(most)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 128.1499939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 132.6499939 58.52199936 Tm [(if)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 138.16499329 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 142.66499329 58.52199936 Tm [(not)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 157.28599548 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 161.78599548 58.52199936 Tm [(all)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 171.55099487 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 176.05099487 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 184.89300537 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 189.39300537 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 203.39399719 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 207.89399719 58.52199936 Tm [(biolo)1(gic)-1(a)1(l)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 249.91000366 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(effec)-1(t)1(s)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 28.48500061 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 32.98500061 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 41.82699966 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 46.32699966 74.12200165 Tm [(th)1(is)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 61.78300095 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 66.28299713 74.12200165 Tm [(cy)-1(t)1(oki)-1(ne.)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 104.7480011 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 109.2480011 74.12200165 Tm [(Ligand)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 138.29600525 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 142.79600525 74.12200165 Tm [(binding)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 175.94000244 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 180.44000244 74.12200165 Tm [(activat)1(es)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 218 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 222.5 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 236.50100708 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 241.00100708 74.12200165 Tm [(rec)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(epto)1(r)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 23.36599922 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 27.86599922 89.72200012 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 54.95399857 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 59.45399857 89.72200012 Tm [(th)1(rough)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 94.35099792 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 98.85099792 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 103.8259964 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 108.3259964 89.72200012 Tm [(pro)1(c)-1(ess)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 141.18400574 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 145.68400574 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 154.52600098 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 159.02600098 89.72200012 Tm [(oligo)1(me)-1(riz)1(ation)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 226.80299377 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 231.30299377 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 247.58000183 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 252.08000183 89.72200012 Tm [(t)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ransp)1(hosp)1(horylat)1(ion.)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 91.06300354 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 95.56300354 105.3219986 Tm [(The)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 111.37000275 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 115.87000275 105.3219986 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 153.3769989 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 157.8769989 105.3219986 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 189.18400574 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 193.68400574 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 200.24499512 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 204.74499512 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 209.72000122 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 214.22000122 105.3219986 Tm [(tyro)1(sin)-1(e)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 248.70799255 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 27.08799934 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 31.58799934 120.92199707 Tm [(tr)1(ansme)-1(mb)1(rane)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 99.84799957 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 104.34799957 120.92199707 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 140.77000427 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 145.27000427 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 161.54699707 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 166.04699707 120.92199707 Tm [(member)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 202.31100464 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 206.81100464 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 215.65299988 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 220.15299988 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 234.15400696 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 238.65400696 120.92199707 Tm [(CSF)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(1/)-1(P)1(DGF)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 32.95899963 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 37.45899963 136.52200317 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 73.8809967 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 78.3809967 136.52200317 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 104.46299744 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 108.96299744 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 117.80500031 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 122.30500031 136.52200317 Tm [(tyro)1(sin)-1(e-p)1(rot)1(e)-1(in)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 191.99299622 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 196.49299622 136.52200317 Tm [(ki)-1(na)1(se)-1(s.)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 229.91299438 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 157.0249939 0.75 l 157.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 158.0249939 -0.25 l 158.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 236 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 237 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.7749939 0.75 m 422.375 0.75 l 422.375 16.35000038 l 157.7749939 16.35000038 l h f* Q q 1 0 0 1 157.3999939 0 cm -0.625 -0.25 m 265.9750061 -0.25 l 265.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 238 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB,)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 16.97200012 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 21.47200012 11.72200012 Tm [(IHC,)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 39.26499939 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 43.76499939 11.72200012 Tm [(IF)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 51.19200134 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 157.5 cm q /GS2 gs 1 g 0.375 0.75 m 157.0249939 0.75 l 157.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 158.0249939 -0.25 l 158.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 244 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 249 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.7749939 0.75 m 422.375 0.75 l 422.375 16.35000038 l 157.7749939 16.35000038 l h f* Q q 1 0 0 1 157.3999939 0 cm -0.625 -0.25 m 265.9750061 -0.25 l 265.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 250 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CSF1)-1(R\(A)1(b-)1(8)-1(09)-1(\))] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 64.96900177 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 173.8500061 cm q /GS2 gs 1 g 0.375 0.75 m 157.0249939 0.75 l 157.0249939 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 158.0249939 -0.25 l 158.0249939 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 252 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 253 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.89400101 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.7749939 0.75 m 422.375 0.75 l 422.375 31.95000076 l 157.7749939 31.95000076 l h f* Q q 1 0 0 1 157.3999939 0 cm -0.625 -0.25 m 265.9750061 -0.25 l 265.9750061 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 254 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Syn)-1(t)1(hesized)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 51.35400009 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 55.85400009 11.72200012 Tm [(non-p)1(hosp)1(hopept)1(ide)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 147.96299744 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 152.46299744 11.72200012 Tm [(derived)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 184.74499512 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 189.24499512 11.72200012 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 209.95599365 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 214.45599365 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 244.49699402 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 248.99699402 11.72200012 Tm [(C)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(SFR)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 15.85099983 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 20.35099983 27.3220005 Tm [(aro)1(u)-1(nd)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 51.33200073 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 55.83200073 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 69.83300018 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 74.33300018 27.3220005 Tm [(ph)1(osph)1(orylation)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 145.10699463 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 149.60699463 27.3220005 Tm [(site)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 164.62800598 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 169.12800598 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 177.97000122 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 182.47000122 27.3220005 Tm [(tyro)1(sin)-1(e)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 216.95799255 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 221.45799255 27.3220005 Tm [(80)-1(9)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 237.29100037 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 241.79100037 27.3220005 Tm [(\(S-)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 205.80000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.3999939 0.75 m 157.3999939 141.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.3999939 141.8999939 m 157.3999939 157.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.3999939 158.25 m 157.3999939 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.3999939 174.6000061 m 157.3999939 205.80000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.75 0.75 m 422.75 205.80000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.125 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 141.5249939 m 422.375 141.5249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.875 m 422.375 157.875 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 174.2250061 m 422.375 174.2250061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 206.17500305 m 423.125 206.17500305 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
endobj
6 0 obj
<</Length1 163 0 R/Length 28648>>stream
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