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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 88 0 cm /P <</Lang (zh-CN) /MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <</MCID 1 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 49.67599869 23.67700005 Tm 0 Tr [(ASH)1(2L)] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 113.23799896 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 223.67799377 23.67700005 Tm 0 Tr [( )] TJ ET EMC /P <</MCID 4 >> BDC BT 1 0 0 -1 228.92799377 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 5 >> BDC BT 1 0 0 -1 -88 43.75799942 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -88 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT 1 0 0 -1 -35.5 61.9640007 Tm [<00030004>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -11.875 61.9640007 Tm [(ASH2L)] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 17.9280014 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 70.42799377 61.9640007 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 75.67799377 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(A)1(S)-1(H2L)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 110.91100311 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 113.28500366 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 138.93499756 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 141.30900574 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 184.86799622 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 187.24200439 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 225.03799438 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ASH2;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 88.57299805 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 90.9469986 12.82499981 Tm [(Bre)1(2;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 113.67500305 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 116.0490036 12.82499981 Tm [(ASH2L1;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 151.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 153.73199463 12.82499981 Tm [(ASH2L2)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 186.23199463 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <</Lang (zh-CN) /MCID 34 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 35 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0014>] TJ ET EMC /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 216.83399963 cm /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0004>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001B000D>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ASH2L)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 90.1780014 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 250.3730011 cm /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 283.9119873 cm /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 317.45098877 cm /P <</Lang (zh-CN) /MCID 66 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002200230024000D>] TJ ET EMC /P <</MCID 67 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 350.98999023 cm /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 384.5289917 m 416.75 384.5289917 l 416.75 415.72900391 l -1.45000005 415.72900391 l h f* Q q 1 0 0 1 0 384.5289917 cm /P <</MCID 77 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 78 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 79 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 415.72900391 cm /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 443.66799927 cm q 1 g 0.375 0.75 m 166.0249939 0.75 l 166.0249939 125.55000305 l 0.375 125.55000305 l h f* Q q -0.625 -0.25 m 167.0249939 -0.25 l 167.0249939 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 81 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 66.3219986 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 66.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 166.7749939 0.75 m 422.42498779 0.75 l 422.42498779 125.55000305 l 166.7749939 125.55000305 l h f* Q q 1 0 0 1 166.3999939 0 cm -0.625 -0.25 m 257.0249939 -0.25 l 257.0249939 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Comp)1(one)-1(nt)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 51.19599915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 55.69599915 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 64.53800201 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 69.03800201 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 83.03900146 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 87.53900146 11.72200012 Tm [(Se)-1(t)1(1)-1(/A)1(sh2)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 131.63400269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 136.13400269 11.72200012 Tm [(hist)1(one)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 167.96400452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 172.46400452 11.72200012 Tm [(methyltr)1(ansferas)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(e)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 5.10599995 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 9.60599995 27.3220005 Tm [(\(HMT)-1(\))] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 36.53099823 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 41.03099823 27.3220005 Tm [(complex,)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 79.67700195 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 84.17700195 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 89.15200043 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 93.65200043 27.3220005 Tm [(complex)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 130.1309967 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 134.6309967 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 151.85299683 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 156.35299683 27.3220005 Tm [(speci)-1(f)1(ic)-1(ally)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 202.83799744 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 207.33799744 27.3220005 Tm [(methylat)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(es)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 9.27200031 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 13.77200031 42.92200089 Tm [('L)-1(ys-)1(4)-1(')] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 41.10599899 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 45.60599899 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 54.44800186 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 58.94800186 42.92200089 Tm [(hist)1(one)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 90.77799988 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 95.27799988 42.92200089 Tm [(H3)-1(,)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 109.68299866 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 114.18299866 42.92200089 Tm [(but)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 128.83000183 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 133.33000183 42.92200089 Tm [(not)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 147.95100403 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 152.45100403 42.92200089 Tm [(if)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 157.96600342 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 162.46600342 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 176.46699524 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 180.96699524 42.92200089 Tm [(ne)-1(ig)1(hbo)1(rin)-1(g)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 233.91700745 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 238.41700745 42.92200089 Tm [('L)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ys-9')] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 20.40800095 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 24.90800095 58.52199936 Tm [(residue)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 56.42100143 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 60.92100143 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 67.48200226 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 71.98200226 58.52199936 Tm [(alread)1(y)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 103.38999939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 107.88999939 58.52199936 Tm [(methylat)1(e)-1(d)1(.)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 158.83999634 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 163.33999634 58.52199936 Tm [(As)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 173.83900452 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 178.33900452 58.52199936 Tm [(pa)1(rt)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 195.85099792 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 200.35099792 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 209.19299316 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 213.69299316 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 227.69400024 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 232.19400024 58.52199936 Tm [(ML)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(L1)-1(/MLL)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 31.77199936 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 36.27199936 74.12200165 Tm [(complex)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 72.75099945 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 77.25099945 74.12200165 Tm [(it)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 82.99900055 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 87.49900055 74.12200165 Tm [(is)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 94.05999756 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 98.55999756 74.12200165 Tm [(involved)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 134.92900085 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 139.42900085 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 147.36999512 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 151.86999512 74.12200165 Tm [(methylat)1(ion)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 203.45300293 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 207.95300293 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 224.22999573 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 228.72999573 74.12200165 Tm [(dim)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ethylat)1(ion)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 43.15000153 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 47.65000153 89.72200012 Tm [(at)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 55.97800064 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 60.47800064 89.72200012 Tm [('L)-1(ys-)1(4)-1(')] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 87.81199646 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 92.31199646 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 101.15399933 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 105.65399933 89.72200012 Tm [(hist)1(one)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 137.48399353 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 141.98399353 89.72200012 Tm [(H3)-1(.)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 156.38900757 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 160.88900757 89.72200012 Tm [(May)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 179.42100525 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 183.92100525 89.72200012 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 219.66200256 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 224.16200256 89.72200012 Tm [(as)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 233.30299377 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 237.80299377 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 242.77799988 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(tr)1(ansc)-1(rip)1(tional)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 61.95399857 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 66.45400238 105.3219986 Tm [(regulat)1(or.)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 108.34700012 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 112.84700012 105.3219986 Tm [(May)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 131.3789978 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 135.8789978 105.3219986 Tm [(play)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 153.75999451 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 158.25999451 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 163.23500061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 167.73500061 105.3219986 Tm [(role)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 184.39500427 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 188.89500427 105.3219986 Tm [(in)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 196.83599854 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 201.33599854 105.3219986 Tm [(hemat)1(opoi)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(esis.)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 18 120.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 125.55000305 cm q 1 g 0.375 0.75 m 166.0249939 0.75 l 166.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 167.0249939 -0.25 l 167.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 203 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 204 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 166.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 166.7749939 16.35000038 l h f* Q q 1 0 0 1 166.3999939 0 cm -0.625 -0.25 m 257.0249939 -0.25 l 257.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 205 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 46.03300095 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 141.8999939 cm q 1 g 0.375 0.75 m 166.0249939 0.75 l 166.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 167.0249939 -0.25 l 167.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 209 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 214 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 166.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 166.7749939 16.35000038 l h f* Q q 1 0 0 1 166.3999939 0 cm -0.625 -0.25 m 257.0249939 -0.25 l 257.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 215 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(ASH2)-1(L)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 28.38400078 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 158.25 cm q 1 g 0.375 0.75 m 166.0249939 0.75 l 166.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 167.0249939 -0.25 l 167.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 217 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 218 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 166.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 166.7749939 16.35000038 l h f* Q q 1 0 0 1 166.3999939 0 cm -0.625 -0.25 m 257.0249939 -0.25 l 257.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 219 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 28.15600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 32.65599823 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 63.96300125 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 68.46299744 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 77.30500031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 81.80500031 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 111.84600067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 116.34600067 11.72200012 Tm [(ASH2)-1(L)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 144.72999573 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 174.60002136 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 166.3999939 0.75 m 166.3999939 125.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 166.3999939 126.30000305 m 166.3999939 141.90000916 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 166.3999939 142.65000916 m 166.3999939 158.25001526 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 166.3999939 159.00001526 m 166.3999939 174.60002136 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 174.60002136 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 125.92500305 m 422.42498779 125.92500305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 142.27500916 m 422.42498779 142.27500916 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 158.62501526 m 422.42498779 158.62501526 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 174.97502136 m 423.17498779 174.97502136 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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