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-110 43.75799942 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -110 61.9640007 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -57.5 61.9640007 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -47 61.9640007 Tm [<00030004>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -23.375 61.9640007 Tm [(ASB9)] TJ ET EMC /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 1.18299866 61.9640007 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 53.68299866 61.9640007 Tm [(   )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 69.43299866 61.9640007 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 82.6780014 cm /P <</Lang (zh-CN) /MCID 13 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 14 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(A)1(S)-1(B9)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 105.66699982 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 108.04100037 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 133.69099426 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 136.06500244 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 179.62399292 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 181.9980011 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 219.79400635 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 116.21700287 cm /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F001000110012000D>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 149.7559967 cm /P <</Lang (zh-CN) /MCID 28 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0004>] TJ ET EMC /P <</MCID 29 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0014000D>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ASB9)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 84.93299866 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 183.29499817 cm /P <</Lang (zh-CN) /MCID 34 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <</MCID 35 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000D>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 216.83399963 cm /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000D>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 250.3730011 cm /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 283.9119873 cm /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0022>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0023>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0024000D>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 317.45098877 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0006000700110025000D>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 88.65000153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 91.02400208 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 134.58299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 350.98999023 m 416.75 350.98999023 l 416.75 382.19000244 l -1.45000005 382.19000244 l h f* Q q 1 0 0 1 0 350.98999023 cm /P <</MCID 68 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 410.1289978 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 72 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 148.7749939 156.75 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 275.0249939 -0.25 l 275.0249939 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 74 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(This)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(anky)-1(rin)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 201.83900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 206.33900452 11.72200012 Tm [(repeat)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 234.06399536 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 238.56399536 11.72200012 Tm [(and)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 254.84100342 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 259.34100342 11.72200012 Tm [(s)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(uppr)1(e)-1(sso)1(r)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 43.07500076 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 47.57500076 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 56.41699982 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 60.91699982 27.3220005 Tm [(cy)-1(t)1(oki)-1(ne)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 97.21600342 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 101.71600342 27.3220005 Tm [(signaling)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 140.64700317 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 145.14700317 27.3220005 Tm [(\(SOCS\))] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 174.9019928 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 179.4019928 27.3220005 Tm [(bo)1(x)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 195.43299866 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 199.93299866 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 231.24000549 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 235.74000549 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 263.98800659 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(Membe)-1(r)1(s)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 40.79000092 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 45.29000092 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 54.13199997 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 58.63199997 42.92200089 Tm [(th)1(is)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 74.08799744 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 78.58799744 42.92200089 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 104.66999817 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 109.16999817 42.92200089 Tm [(can)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 124.20400238 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 128.70399475 42.92200089 Tm [(interact)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 161.38200378 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 165.88200378 42.92200089 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 184.27799988 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 188.77799988 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 202.77900696 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 207.27900696 42.92200089 Tm [(elongin)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 239.7460022 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 244.2460022 42.92200089 Tm [(B-C)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 259.80700684 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ad)1(apt)1(e)-1(r)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 33.34999847 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 37.84999847 58.52199936 Tm [(complex)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 74.32900238 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 78.82900238 58.52199936 Tm [(via)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 90.92299652 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 95.42299652 58.52199936 Tm [(th)1(e)-1(ir)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 115.2559967 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 119.7559967 58.52199936 Tm [(SOCS)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 143.5 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 148 58.52199936 Tm [(bo)1(x)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 164.03100586 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 168.53100586 58.52199936 Tm [(do)1(main)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 201.35800171 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 205.85800171 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 222.13499451 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 226.63499451 58.52199936 Tm [(furt)1(her)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 256.17498779 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 260.67498779 58.52199936 Tm [(c)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(omp)1(l)-1(ex)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 31.9659996 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 36.4659996 74.12200165 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 54.86199951 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 59.36199951 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 73.36299896 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 77.86299896 74.12200165 Tm [(cu)-1(llin)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 100.65299988 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 105.15299988 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 121.43000031 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 125.93000031 74.12200165 Tm [(ring)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 143.06399536 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 147.56399536 74.12200165 Tm [(bo)1(x)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 163.59500122 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 168.09500122 74.12200165 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 203.56799316 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 208.06799316 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 217.14300537 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 221.64300537 74.12200165 Tm [(fo)1(rm)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 242.35400391 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 246.85400391 74.12200165 Tm [(E3)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 257.07998657 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ubiquitin)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 38.68099976 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 43.18099976 89.72200012 Tm [(ligas)1(e)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 67.97499847 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 72.47499847 89.72200012 Tm [(complexe)-1(s)1(.)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 120.39299774 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 124.89299774 89.72200012 Tm [(They)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 145.46400452 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 149.96400452 89.72200012 Tm [(may)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 168.13499451 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 172.63499451 89.72200012 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 208.37600708 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 212.87600708 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 221.95100403 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 226.45100403 89.72200012 Tm [(mediat)1(e)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 261.57598877 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 14.0010004 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 18.50099945 105.3219986 Tm [(subst)1(rat)1(e)-1(-)1(re)-1(cog)1(n)-1(it)1(ion)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 111.73500061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 116.23500061 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 125.07700348 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 129.57699585 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 143.57800293 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 148.07800293 105.3219986 Tm [(E3)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 158.30400085 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 162.80400085 105.3219986 Tm [(ubiquitin)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 201.48500061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 205.98500061 105.3219986 Tm [(ligas)1(e)-1(s.)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 237.11099243 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 241.61099243 105.3219986 Tm [(A)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 247.94400024 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 252.44400024 105.3219986 Tm [(tr)1(a)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(nsc)-1(r)1(i)-1(b)1(e)-1(d)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 36.66799927 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 41.16799927 120.92199707 Tm [(pseudog)1(e)-1(ne)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 94.72899628 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 99.22899628 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 108.07099915 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 112.57099915 120.92199707 Tm [(th)1(is)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 128.0269928 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 132.5269928 120.92199707 Tm [(gene)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 154.04299927 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 158.54299927 120.92199707 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 173.2250061 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 177.7250061 120.92199707 Tm [(been)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 199.23199463 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 203.73199463 120.92199707 Tm [(identified)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 244.66299438 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 249.16299438 120.92199707 Tm [(on)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 260.43099976 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 56.79499817 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 61.29499817 136.52200317 Tm [(15)-1(.)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 74.01699829 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 78.51699829 136.52200317 Tm [(Multiple)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 114.24900055 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 118.74900055 136.52200317 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 159.67100525 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 164.17100525 136.52200317 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 197.74099731 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 202.24099731 136.52200317 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 242.58299255 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 247.08299255 136.52200317 Tm [(dif)1(fe)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(rent)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 17.44199944 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 21.94199944 152.12199402 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 59.10200119 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 63.60200119 152.12199402 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 83.9489975 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 88.4489975 152.12199402 Tm [(been)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 109.95600128 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 114.45600128 152.12199402 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 140.14599609 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 144.64599609 152.12199402 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 156.92399597 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 161.42399597 152.12199402 Tm [(th)1(is)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 176.88000488 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 181.38000488 152.12199402 Tm [(gene)-1(.)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 205.06199646 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 252 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 253 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 275.0249939 -0.25 l 275.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 254 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(WB,)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 47.37799835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 51.87799835 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 67.50499725 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 173.1000061 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 260 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 265 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 275.0249939 -0.25 l 275.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 266 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(ASB9)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 22.45199966 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 189.44999695 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 149.0249939 -0.25 l 149.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 268 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 269 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm -0.625 -0.25 m 275.0249939 -0.25 l 275.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 270 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Ful)-1(l)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 15.11699963 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 19.61700058 11.72200012 Tm [(len)-1(g)1(th)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 47.31600189 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 51.81600189 11.72200012 Tm [(fusion)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 78.31099701 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 82.81099701 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 114.11799622 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 205.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 0.75 m 148.3999939 156.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 157.5 m 148.3999939 173.1000061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 173.8500061 m 148.3999939 189.45001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 190.20001221 m 148.3999939 205.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 205.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 173.4750061 m 422.42498779 173.4750061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 189.82501221 m 422.42498779 189.82501221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 206.17501831 m 423.17498779 206.17501831 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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