ELISA試劑盒分局多能干細(xì)胞

<p class="MsoNormal"><strong><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;">ELISA<font face="宋體">試劑盒</font></span></strong><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><font face="宋體">胚胎干細(xì)胞被稱為多能干細(xì)胞，因?yàn)樗麄冇凶晕腋履芰?，并有成為體內(nèi)任何細(xì)胞的潛力。研究人員希望了解組成小鼠胚胎內(nèi)細(xì)胞群細(xì)胞的干細(xì)胞和外胚層或植入階段細(xì)胞之間的區(qū)別。在外胚層階段的小鼠胚胎干細(xì)胞更接近于人類胚胎干細(xì)胞、癌細(xì)胞。</font></span><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><o:p></o:p></span></p> <p class="MsoNormal"><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><font face="宋體">人干細(xì)胞和小鼠外胚層干細(xì)胞比老鼠發(fā)育早期的干細(xì)胞具有較低的線粒體呼吸活性。盡管事實(shí)上，</font><strong>ELISA<font face="宋體">試劑盒</font></strong><font face="宋體">發(fā)育后期干細(xì)胞線粒體較成熟后，線粒體呼吸活性會降低。</font></span><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><o:p></o:p></span></p> <p class="MsoNormal"><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;">研究人員證實(shí)在內(nèi)細(xì)胞群細(xì)胞轉(zhuǎn)變成外胚層細(xì)胞的過渡期間，某些基因控制線粒體細(xì)胞呼吸活性的降低。</span><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><o:p></o:p></span></p> <p class="MsoNormal"><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;">相反，過渡期細(xì)胞獲得能量完全不依賴于糖、葡萄糖。相比之下，早期小鼠胚胎干細(xì)胞通過將線粒體呼吸動(dòng)態(tài)切換到葡萄糖分解后，能獲得更多能量。</span><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><o:p></o:p></span></p> <p class="MsoNormal"><strong><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;">ELISA<font face="宋體">試劑盒</font></span></strong><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><font face="宋體">研究人員發(fā)現(xiàn)低氧條件下激活的轉(zhuǎn)錄因子是缺氧誘導(dǎo)因子</font><font face="Calibri">1</font><font face="宋體">&alpha;。缺氧誘導(dǎo)因子</font><font face="Calibri">1</font><font face="宋體">&alpha;足夠推動(dòng)小鼠胚胎干細(xì)胞完全依靠糖代謝來獲取能量。下一個(gè)挑戰(zhàn)是揭示在正常生理情況以及在癌癥情況下這種代謝轉(zhuǎn)化是否對干細(xì)胞的命運(yùn)也有決定性影響。</font></span><span style="mso-spacerun:'yes';font-family:宋體;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;mso-bidi-font-family:'Times New Roman';font-size:9.0000pt;mso-font-kerning:1.0000pt;"><o:p></o:p></span></p>